Literature DB >> 32557631

Regenerative potential of Wharton's jelly-derived mesenchymal stem cells: A new horizon of stem cell therapy.

Hossein Abbaszadeh1,2, Farzaneh Ghorbani1,2, Mehdi Derakhshani1,2, Ali Akbar Movassaghpour3, Mehdi Yousefi4, Mehdi Talebi5, Karim Shamsasenjan2.   

Abstract

Umbilical cord Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) have recently gained considerable attention in the field of regenerative medicine. Their high proliferation rate, differentiation ability into various cell lineages, easy collection procedure, immuno-privileged status, nontumorigenic properties along with minor ethical issues make them an ideal approach for tissue repair. Besides, the number of WJ-MSCs in the umbilical cord samples is high as compared to other sources. Because of these properties, WJ-MSCs have rapidly advanced into clinical trials for the treatment of a wide range of disorders. Therefore, this paper summarized the current preclinical and clinical studies performed to investigate the regenerative potential of WJ-MSCs in neural, myocardial, skin, liver, kidney, cartilage, bone, muscle, and other tissue injuries.
© 2020 Wiley Periodicals LLC.

Keywords:  Wharton's jelly; mesenchymal stem cells; regenerative medicine; umbilical cord

Mesh：

Year:  2020        PMID： 32557631     DOI： 10.1002/jcp.29810

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN： 0021-9541            Impact factor:   6.384


  10 in total

1.  Development of a novel feeding regime for large scale production of human umbilical cord mesenchymal stem/stromal cells.

Authors:  Yichen Dai; Xiaolin Cui; Ge Zhang; Ali Mohsin; Huiming Xu; Yingping Zhuang; Meijin Guo
Journal:  Cytotechnology       Date:  2022-03-10       Impact factor: 2.040

Review 2.  Chronic obstructive pulmonary disease and asthma: mesenchymal stem cells and their extracellular vesicles as potential therapeutic tools.

Authors:  Hossein Abbaszadeh; Farzaneh Ghorbani; Sanaz Abbaspour-Aghdam; Amin Kamrani; Hamed Valizadeh; Mehdi Nadiri; Armin Sadeghi; Karim Shamsasenjan; Farhad Jadidi-Niaragh; Leila Roshangar; Majid Ahmadi
Journal:  Stem Cell Res Ther       Date:  2022-06-20       Impact factor: 8.079

Review 3.  Shining the light on clinical application of mesenchymal stem cell therapy in autoimmune diseases.

Authors:  Saade Abdalkareem Jasim; Alexei Valerievich Yumashev; Walid Kamal Abdelbasset; Ria Margiana; Alexander Markov; Wanich Suksatan; Benjamin Pineda; Lakshmi Thangavelu; Seyed Hossein Ahmadi
Journal:  Stem Cell Res Ther       Date:  2022-03-07       Impact factor: 6.832

4.  Co-culture pellet of human Wharton's jelly mesenchymal stem cells and rat costal chondrocytes as a candidate for articular cartilage regeneration: in vitro and in vivo study.

Authors:  Kaiwen Zheng; Yiyang Ma; Cheng Chiu; Yidan Pang; Junjie Gao; Changqing Zhang; Dajiang Du
Journal:  Stem Cell Res Ther       Date:  2022-07-30       Impact factor: 8.079

Review 5.  Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review.

Authors:  Ria Margiana; Alexander Markov; Angelina O Zekiy; Mohammed Ubaid Hamza; Khalid A Al-Dabbagh; Sura Hasan Al-Zubaidi; Noora M Hameed; Irshad Ahmad; R Sivaraman; Hamzah H Kzar; Moaed E Al-Gazally; Yasser Fakri Mustafa; Homayoon Siahmansouri
Journal:  Stem Cell Res Ther       Date:  2022-07-28       Impact factor: 8.079

Review 6.  Role of hypoxia preconditioning in therapeutic potential of mesenchymal stem-cell-derived extracellular vesicles.

Authors:  Victoria Pulido-Escribano; Bárbara Torrecillas-Baena; Marta Camacho-Cardenosa; Gabriel Dorado; María Ángeles Gálvez-Moreno; Antonio Casado-Díaz
Journal:  World J Stem Cells       Date:  2022-07-26       Impact factor: 5.247

7.  NR2F2 Regulates Cell Proliferation and Immunomodulation in Whartons' Jelly Stem Cells.

Authors:  Li Ma; Min Huang; Xiaohua Liao; Xiyu Cai; Qiang Wu
Journal:  Genes (Basel)       Date:  2022-08-16       Impact factor: 4.141

8.  Gene Expression Profiles of Human Mesenchymal Stromal Cells Derived from Wharton's Jelly and Amniotic Membrane before and after Osteo-Induction Using NanoString Platform.

Authors:  Vun Vun Hiew; Haselamirrah Mohd Akhir; Peik Lin Teoh
Journal:  Curr Issues Mol Biol       Date:  2022-09-14       Impact factor: 2.976

9.  Human Platelet Lysate Supports Efficient Expansion and Stability of Wharton's Jelly Mesenchymal Stromal Cells via Active Uptake and Release of Soluble Regenerative Factors.

Authors:  Mariana Cañas-Arboleda; Karl Beltrán; Carlos Medina; Bernardo Camacho; Gustavo Salguero
Journal:  Int J Mol Sci       Date:  2020-08-31       Impact factor: 5.923

10.  Vascular Remodeling of Clinically Used Patches and Decellularized Pericardial Matrices Recellularized with Autologous or Allogeneic Cells in a Porcine Carotid Artery Model.

Authors:  Jaroslav Chlupac; Roman Matejka; Miroslav Konarik; Robert Novotny; Zuzana Simunkova; Iveta Mrazova; Ondrej Fabian; Milan Zapletal; Zdenek Pulda; Jan Falk Lipensky; Jana Stepanovska; Karel Hanzalek; Antonin Broz; Tomas Novak; Alena Lodererova; Ludek Voska; Theodor Adla; Jiri Fronek; Miroslav Rozkot; Serhiy Forostyak; Peter Kneppo; Lucie Bacakova; Jan Pirk
Journal:  Int J Mol Sci       Date:  2022-03-18       Impact factor: 5.923
  10 in total

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