Literature DB >> 32555602

Correction: Evaluation of nitazoxanide treatment following triclabendazole failure in an outbreak of human fascioliasis in Upper Egypt.

Haidi Karam-Allah Ramadan, Waleed Attia Hassan, Nahed Ahmed Elossily, Alzahraa Abdelraouf Ahmad, Adnan Ahmed Mohamed, Alaa Soliman Abd-Elkader, Eman M Nagiub Abdelsalam, Hani M J Khojah.   

Abstract

[This corrects the article DOI: 10.1371/journal.pntd.0007779.].

Entities:  

Year:  2020        PMID: 32555602      PMCID: PMC7299317          DOI: 10.1371/journal.pntd.0008443

Source DB:  PubMed          Journal:  PLoS Negl Trop Dis        ISSN: 1935-2727


In the methodology section of the abstract the term “pathological” was used incorrectly and should be “biochemical” instead. The corrected sentence reads: “The remaining cases received additional doses of TCBZ with complete clinical, biochemical, and radiological resolution.” There is a typographical error in the footnote of Table 5. In the updated Table 5, the reference range for platelet count in the footnote has been updated to 150,000–450,000/µL.
Table 5

Laboratory data of the studied patients who received first line triclabendazole.

Non- responders to TCBZ(n = 30)Responders to TCBZ(n = 37)P value
Mean ± SDMean ± SD
Hb level (g/dl):11.80 ± 1.1311.81 ± 0.900.930
WBCs (cells/µL):17.46 ± 12.2510.27 ± 3.920.008*
Eosinophils % before treatment26.72 ± 13.21Range = 14–40%30.47 ± 15.18Range = 7–70%0.081
Eosinophils % after treatment20.00 ± 11.28Range = 3–59%3.6 ± 1.7Range = 1–15%0.0001*
PLT (cells/µL)311.60 ± 85.07308.11 ± 75.790.796
Total bilirubin (mg/dl)1.04 ± 0.151.06 ± 0.170.613
ALT (IU/L)61.43 ± 43.4439.62 ± 18.520.026*
AST (IU/L)53.83 ± 36.0535.78 ± 15.840.047*
Positive stool analysis2 (6.7%)5 (13.5%)0.447
Serology titer885.33 ± 391.32977.30 ± 384.190.338

Hb, hemoglobin; WBCs, white blood cells; PLT, platelets count; ALT, alanine aminotransferase; AST, aspartate aminotransferase.

Reference ranges: Hb (male) = 14–17 g/dL; Hb (female) = 12–16 g/dL; WBCs = 4000–10,000/μL; eosinophils = 0–5%; PLT count = 150,000–450,000/μL; total bilirubin = 0.3–1.2 mg/dL; ALT = 0–35 IU/L; AST = 0–35 IU/L. Serology titer ≥ 1/320 is considered positive.

* Significant p-value by Fisher exact test.

Hb, hemoglobin; WBCs, white blood cells; PLT, platelets count; ALT, alanine aminotransferase; AST, aspartate aminotransferase. Reference ranges: Hb (male) = 14–17 g/dL; Hb (female) = 12–16 g/dL; WBCs = 4000–10,000/μL; eosinophils = 0–5%; PLT count = 150,000–450,000/μL; total bilirubin = 0.3–1.2 mg/dL; ALT = 0–35 IU/L; AST = 0–35 IU/L. Serology titer ≥ 1/320 is considered positive. * Significant p-value by Fisher exact test.
  1 in total

1.  Evaluation of nitazoxanide treatment following triclabendazole failure in an outbreak of human fascioliasis in Upper Egypt.

Authors:  Haidi Karam-Allah Ramadan; Waleed Attia Hassan; Nahed Ahmed Elossily; Alzahraa Abdelraouf Ahmad; Adnan Ahmed Mohamed; Alaa Soliman Abd-Elkader; Eman M Nagiub Abdelsalam; Hani M J Khojah
Journal:  PLoS Negl Trop Dis       Date:  2019-09-25
  1 in total

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