| Literature DB >> 32555302 |
Christiaan Delmaar1, Joris Meesters2.
Abstract
To ensure safe use of chemical substances in consumer products, the exposure of consumers to these substances needs to be evaluated. For this purpose, generally consumer exposure modeling tools are used. To build confidence in such tools, evaluation of their performance with experimental data is indispensable. This work describes the evaluation of two consumer exposure modeling tools: ConsExpo Web and ConsExpo nano. Both models contain a module to estimate exposure of substances released as an aerosol during the use of spray products. This particular model was tested by comparing measured exposure data with model simulations. Experimental data were obtained from the public literature. These typically provide measured air concentrations under simulated use conditions of spray products. ConsExpo Web and ConsExpo nano were used to simulate experimental settings of the different studies. The resulting simulated air concentrations were compared with the reported ones. Overall, good agreement between modeled and measured data was observed. However, a significant proportion of the studies considered, did not provide sufficient detail in the specification of the experimental conditions to make them suitable for model evaluation. Critical information that was often lacking was on product composition, the mass sprayed during usage, and the generated aerosol size distribution.Year: 2020 PMID: 32555302 DOI: 10.1038/s41370-020-0239-x
Source DB: PubMed Journal: J Expo Sci Environ Epidemiol ISSN: 1559-0631 Impact factor: 5.563