Literature DB >> 32554811

Infant With SARS-CoV-2 Infection Causing Severe Lung Disease Treated With Remdesivir.

Claire Frauenfelder1,2, Joe Brierley1, Elizabeth Whittaker3, Giulia Perucca1, Alasdair Bamford4,5.   

Abstract

We describe an ex-premature infant presenting with severe acute respiratory syndrome coronavirus 2 infection in the fifth week of life. In current reports, researchers indicate that acute symptomatic severe acute respiratory syndrome coronavirus 2 infection is relatively rare and much less severe than in adults. This case highlights that infection can be associated with life-threatening pulmonary disease in young infants and that infection can follow a similar disease course to that described in adults. We provide first data on the use of the novel antiviral remdesivir in a young child and an innovative approach to expedited approval from a multidisciplinary clinical team and bioethics committee for compassionate access to the drug.
Copyright © 2020 by the American Academy of Pediatrics.

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Year:  2020        PMID: 32554811     DOI: 10.1542/peds.2020-1701

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  15 in total

Review 1.  COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials.

Authors:  Ramon Galindo; Heather Chow; Chokechai Rongkavilit
Journal:  Pediatr Clin North Am       Date:  2021-05-18       Impact factor: 3.278

2.  Management and Outcome of Coronavirus Disease 2019 (COVID-19) in Pediatric Cancer Patients: A Single Centre Experience from a Developing Country.

Authors:  Mahmoud Hammad; Lobna Shalaby; Iman Sidhom; Nancy Sherief; Ibrahim Abdo; Sonia Soliman; Youssef Madeny; Reem Hassan; Shaimaa Elmeniawy; Nagwa Khamis; Iman Zaki; Tarek Mansour; Mohamed Gamal El-Ansary; Ahmed Al-Halfawy; Sherif Abouelnaga; Alaa Elhaddad
Journal:  Clin Lymphoma Myeloma Leuk       Date:  2021-07-26

3.  Evolution of viral variants in remdesivir-treated and untreated SARS-CoV-2-infected pediatrics patients.

Authors:  Florencia A T Boshier; Juanita Pang; Justin Penner; Matthew Parker; Nele Alders; Alasdair Bamford; Louis Grandjean; Stephanie Grunewald; James Hatcher; Timothy Best; Caroline Dalton; Patricia Dyal Bynoe; Claire Frauenfelder; Jutta Köeglmeier; Phoebe Myerson; Sunando Roy; Rachel Williams; Thushan I de Silva; Richard A Goldstein; Judith Breuer
Journal:  J Med Virol       Date:  2021-09-04       Impact factor: 20.693

Review 4.  Cigarette Smoke Exposure, Pediatric Lung Disease, and COVID-19.

Authors:  Marta Schiliro; Elizabeth R Vogel; Lucia Paolini; Christina M Pabelick
Journal:  Front Physiol       Date:  2021-04-27       Impact factor: 4.566

5.  COVID-19, children, clinical trials and compassion: The ethical case for using innovative or compassionate treatments.

Authors:  Vic Larcher; Art Caplan; Joe Brierley
Journal:  Acta Paediatr       Date:  2021-10-28       Impact factor: 4.056

Review 6.  Neonatal SARS-CoV-2 Infection: Practical Tips.

Authors:  Cinzia Auriti; Domenico Umberto De Rose; Vito Mondì; Ilaria Stolfi; Chryssoula Tzialla
Journal:  Pathogens       Date:  2021-05-17

7.  Comparison of Clinical and Epidemiologic Characteristics of Young Febrile Infants with and without Severe Acute Respiratory Syndrome Coronavirus-2 Infection.

Authors:  Jill Leibowitz; William Krief; Stephen Barone; Kristy A Williamson; Pratichi K Goenka; Shipra Rai; Shannon Moriarty; Prachi Baodhankar; Lorry G Rubin
Journal:  J Pediatr       Date:  2020-10-09       Impact factor: 4.406

8.  Transmission of SARS-CoV-2 through breast milk and breastfeeding: a living systematic review.

Authors:  Elizabeth Centeno-Tablante; Melisa Medina-Rivera; Julia L Finkelstein; Pura Rayco-Solon; Maria Nieves Garcia-Casal; Lisa Rogers; Kate Ghezzi-Kopel; Pratiwi Ridwan; Juan Pablo Peña-Rosas; Saurabh Mehta
Journal:  Ann N Y Acad Sci       Date:  2020-08-28       Impact factor: 5.691

9.  Epidemiologic and clinical characteristics of neonates with late-onset COVID-19: 1-year data of Turkish Neonatal Society.

Authors:  Ilke Mungan Akin; Mehmet Kenan Kanburoglu; Cuneyt Tayman; Mehmet Yekta Oncel; Timucin Imdadoglu; Mustafa Dilek; Akan Yaman; Fatma Narter; Ilkay Er; Hasan Kahveci; Omer Erdeve; Esin Koc
Journal:  Eur J Pediatr       Date:  2022-01-21       Impact factor: 3.860

10.  Severe COVID-19 Complicated by Cerebral Venous Thrombosis in a Newborn Successfully Treated with Remdesivir, Glucocorticoids, and Hyperimmune Plasma.

Authors:  Laura Cursi; Francesca Ippolita Calo Carducci; Sara Chiurchiu; Lorenza Romani; Francesca Stoppa; Giulia Lucignani; Cristina Russo; Daniela Longo; Carlo Federico Perno; Corrado Cecchetti; Mary Haywood Lombardi; Patrizia D'Argenio; Laura Lancella; Stefania Bernardi; Paolo Rossi
Journal:  Int J Environ Res Public Health       Date:  2021-12-15       Impact factor: 3.390

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