Literature DB >> 32553966

Emulsion-based delivery systems for curcumin: Encapsulation and interaction mechanism between debranched starch and curcumin.

Tao Feng1, Zhongshan Hu2, Ke Wang3, Xiao Zhu4, Da Chen5, Haining Zhuang6, Lingyun Yao2, Shiqing Song2, Huatian Wang2, Min Sun2.   

Abstract

Curcumin has been widely recognized as health-promoting compound. However, the intrinsic hydrophobicity, chemical instability and photodegradation limits its applications in foods. In this study, a novel emulsion was developed to encapsulate curcumin using debranched starch (DBS). The encapsulation efficiency of curcumin was 71.11% with a loading rate of 12.07%. The prepared emulsions showed better stability and solubility of curcumin than those stabilized only with Tween80 and lectin. The DBS incorporated emulsion had a uniform droplet size distribution with an average value of <1 μm. The molecular dynamics (MD) simulation showed that the water bridge between debranched starch and curcumin may play an important role in the complexation process, thus contributing to a better performance of the emulsion. This work shed light on the encapsulation process and interaction between DBS and curcumin, which is valuable to develop new emulsion-based delivery systems for bioactive lipophilic compounds using modified starch.
Copyright © 2020 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Curcumin; Debranched starch; Emulsion; Interaction mechanism; Molecular dynamics simulation

Year:  2020        PMID: 32553966     DOI: 10.1016/j.ijbiomac.2020.06.088

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN: 0141-8130            Impact factor:   6.953


  2 in total

1.  Poly(vinyl alcohol)-tannic Acid Cryogel Matrix as Antioxidant and Antibacterial Material.

Authors:  Betul Ari; Mehtap Sahiner; Sahin Demirci; Nurettin Sahiner
Journal:  Polymers (Basel)       Date:  2021-12-25       Impact factor: 4.329

Review 2.  Progress in Colloid Delivery Systems for Protection and Delivery of Phenolic Bioactive Compounds: Two Study Cases-Hydroxytyrosol and Curcumin.

Authors:  Francesca Cuomo; Silvio Iacovino; Pasquale Sacco; Antonella De Leonardis; Andrea Ceglie; Francesco Lopez
Journal:  Molecules       Date:  2022-01-29       Impact factor: 4.411

  2 in total

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