Literature DB >> 32551406

Molecular and electrophysiological properties of mouse motoneuron and motor unit subtypes.

Marin Manuel1, Daniel Zytnicki1.   

Abstract

The field of motoneuron and motor unit physiology in mammals has deeply evolved the last decade thanks to the parallel development of mouse genetics and transcriptomic analysis and of in vivo mouse preparations that allow intracellular electrophysiological recordings of motoneurons. We review the efforts made to investigate the electrophysiological properties of the different functional subtypes of mouse motoneurons, to decipher the mosaic of molecular markers specifically expressed in each subtype, and to elucidate which of those factors drive the identity of motoneurons.

Entities:  

Keywords:  Functional diversity of spinal motoneurons; In vitro and in vivo spinal cord electrophysiology; Molecular markers; Spinal motor system

Year:  2018        PMID： 32551406      PMCID： PMC7302113          DOI： 10.1016/j.cophys.2018.11.008

Source DB:  PubMed          Journal:  Curr Opin Physiol        ISSN： 2468-8673


  50 in total

1.  An in vitro spinal cord slice preparation for recording from lumbar motoneurons of the adult mouse.

Authors:  Pratip Mitra; Robert M Brownstone
Journal:  J Neurophysiol       Date:  2011-10-26       Impact factor: 2.714

2.  Adult mouse motor units develop almost all of their force in the subprimary range: a new all-or-none strategy for force recruitment?

Authors:  Marin Manuel; C J Heckman
Journal:  J Neurosci       Date:  2011-10-19       Impact factor: 6.167

3.  Identification of novel spinal cholinergic genetic subtypes disclose Chodl and Pitx2 as markers for fast motor neurons and partition cells.

Authors:  Anders Enjin; Nadine Rabe; Stan T Nakanishi; Anna Vallstedt; Henrik Gezelius; Fatima Memic; Magnus Lind; Tord Hjalt; Warren G Tourtellotte; Carl Bruder; Gregor Eichele; Patrick J Whelan; Klas Kullander
Journal:  J Comp Neurol       Date:  2010-06-15       Impact factor: 3.215

4.  Fictive locomotion in the adult decerebrate and spinal mouse in vivo.

Authors:  C F Meehan; L Grondahl; J B Nielsen; H Hultborn
Journal:  J Physiol       Date:  2011-11-21       Impact factor: 5.182

5.  Calcitonin gene-related peptide expression levels predict motor neuron vulnerability in the superoxide dismutase 1-G93A mouse model of amyotrophic lateral sclerosis.

Authors:  Cornelia Ringer; Eberhard Weihe; Burkhard Schütz
Journal:  Neurobiol Dis       Date:  2011-09-21       Impact factor: 5.996

6.  Potassium currents dynamically set the recruitment and firing properties of F-type motoneurons in neonatal mice.

Authors:  Félix Leroy; Boris Lamotte d'Incamps; Daniel Zytnicki
Journal:  J Neurophysiol       Date:  2015-08-12       Impact factor: 2.714

7.  Fast kinetics, high-frequency oscillations, and subprimary firing range in adult mouse spinal motoneurons.

Authors:  Marin Manuel; Caroline Iglesias; Maud Donnet; Félix Leroy; C J Heckman; Daniel Zytnicki
Journal:  J Neurosci       Date:  2009-09-09       Impact factor: 6.167

8.  Kv1.2 Channels Promote Nonlinear Spiking Motoneurons for Powering Up Locomotion.

Authors:  Rémi Bos; Ronald M Harris-Warrick; Cécile Brocard; Liliia E Demianenko; Marin Manuel; Daniel Zytnicki; Sergiy M Korogod; Frédéric Brocard
Journal:  Cell Rep       Date:  2018-03-20       Impact factor: 9.423

9.  Developing electrical properties of postnatal mouse lumbar motoneurons.

Authors:  Jacques Durand; Anton Filipchuk; Arnaud Pambo-Pambo; Julien Amendola; Iryna Borisovna Kulagina; Jean-Patrick Guéritaud
Journal:  Front Cell Neurosci       Date:  2015-09-02       Impact factor: 5.505

10.  Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS.

Authors:  María de Lourdes Martínez-Silva; Rebecca D Imhoff-Manuel; Aarti Sharma; C J Heckman; Neil A Shneider; Francesco Roselli; Daniel Zytnicki; Marin Manuel
Journal:  Elife       Date:  2018-03-27       Impact factor: 8.140
View more
  2 in total

1.  Recruitment of Motoneurons.

Authors:  Vatsala Thirumalai; Urvashi Jha
Journal:  Adv Neurobiol       Date:  2022

Review 2.  The Role and Modulation of Spinal Perineuronal Nets in the Healthy and Injured Spinal Cord.

Authors:  Judith Sánchez-Ventura; Michael A Lane; Esther Udina
Journal:  Front Cell Neurosci       Date:  2022-05-20       Impact factor: 6.147
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.