Literature DB >> 32549945

Hyponatremia in the Neurologically Ill Patient: A Review.

David P Lerner1, Starane A Shepherd2, Ayush Batra3.   

Abstract

Hyponatremia is a well-known disorder commonly faced by clinicians managing neurologically ill patients. Neurological disorders are often associated with hyponatremia during their acute presentation and can be associated with specific neurologic etiologies and symptoms. Patients may present with hyponatremia with traumatic brain injury, develop hyponatremia subacutely following aneurysmal subarachnoid hemorrhage, or may manifest with seizures due to hyponatremia itself. Clinicians caring for the neurologically ill patient should be well versed in identifying these early signs, symptoms, and etiologies of hyponatremia. Early diagnosis and treatment can potentially avoid neurologic and systemic complications in these patients and improve outcomes. This review focuses on the causes and findings of hyponatremia in the neurologically ill patient and discusses the pathophysiology, diagnoses, and treatment strategies for commonly encountered etiologies.
© The Author(s) 2020.

Entities:  

Keywords:  SIADH; cerebral salt wasting; encephalopathy; hyponatremia; sodium

Year:  2020        PMID: 32549945      PMCID: PMC7271621          DOI: 10.1177/1941874419895124

Source DB:  PubMed          Journal:  Neurohospitalist        ISSN: 1941-8744


  73 in total

Review 1.  Brain volume regulation in response to changes in osmolality.

Authors:  J G Verbalis
Journal:  Neuroscience       Date:  2010-04-24       Impact factor: 3.590

Review 2.  Cerebral salt wasting: pathophysiology, diagnosis, and treatment.

Authors:  Alan H Yee; Joseph D Burns; Eelco F M Wijdicks
Journal:  Neurosurg Clin N Am       Date:  2010-04       Impact factor: 2.509

Review 3.  Electrolytes disturbances and seizures.

Authors:  Luis Castilla-Guerra; María del Carmen Fernández-Moreno; José Manuel López-Chozas; Ricardo Fernández-Bolaños
Journal:  Epilepsia       Date:  2006-12       Impact factor: 5.864

Review 4.  Clinical practice. The syndrome of inappropriate antidiuresis.

Authors:  David H Ellison; Tomas Berl
Journal:  N Engl J Med       Date:  2007-05-17       Impact factor: 91.245

5.  Open-label randomized trial of the safety and efficacy of a single dose conivaptan to raise serum sodium in patients with traumatic brain injury.

Authors:  Christopher Galton; Steven Deem; N David Yanez; Michael Souter; Randall Chesnut; Armagan Dagal; Miriam Treggiari
Journal:  Neurocrit Care       Date:  2011-06       Impact factor: 3.210

Review 6.  Use of hypertonic saline solutions in treatment of cerebral edema and intracranial hypertension.

Authors:  A I Qureshi; J I Suarez
Journal:  Crit Care Med       Date:  2000-09       Impact factor: 7.598

Review 7.  Osmotic demyelination syndrome: central pontine myelinolysis and extrapontine myelinolysis.

Authors:  Anthony M Alleman
Journal:  Semin Ultrasound CT MR       Date:  2013-09-28       Impact factor: 1.875

Review 8.  A review of drug-induced hyponatremia.

Authors:  George Liamis; Haralampos Milionis; Moses Elisaf
Journal:  Am J Kidney Dis       Date:  2008-05-12       Impact factor: 8.860

9.  A randomized controlled trial of hydrocortisone against hyponatremia in patients with aneurysmal subarachnoid hemorrhage.

Authors:  Yoichi Katayama; Jo Haraoka; Hidehiro Hirabayashi; Tatsuro Kawamata; Keiji Kawamoto; Takao Kitahara; Jun Kojima; Toshihiko Kuroiwa; Tatsuro Mori; Nobuhiro Moro; Izumi Nagata; Akira Ogawa; Kikuo Ohno; Yoshikatsu Seiki; Yoshiaki Shiokawa; Akira Teramoto; Teiji Tominaga; Toshiki Yoshimine
Journal:  Stroke       Date:  2007-06-21       Impact factor: 7.914

10.  Volume depletion and natriuresis in patients with a ruptured intracranial aneurysm.

Authors:  E F Wijdicks; M Vermeulen; J A ten Haaf; A Hijdra; W H Bakker; J van Gijn
Journal:  Ann Neurol       Date:  1985-08       Impact factor: 10.422

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