Literature DB >> 32549844

Hormonal Regulation In Pcos Using Acupuncture And Herbal Supplements: A Case Report And Review Of The Literature.

Marika Alois1, Irene M Estores2.   

Abstract

Polycystic ovarian syndrome (PCOS) is a common cause of menstrual irregularity and hyperandrogenism in women of reproductive age. Conventional treatment is centered around the use of oral contraceptive pills (OCPs) to regulate menstrual cycles, protect against endometrial hyperplasia, and manage clinically evident androgen excess. Many women prefer to avoid OCPs due to concerns about risks and adverse effects, or simply because they desire a non-pharmacologic approach. We present the case of a young woman with a strong preference for a natural approach to her care who presented with PCOS manifesting in menstrual irregularity, acne, and hirsutism. In this case, acupuncture as well as the botanicals Vitex agnus-castus and diindolylmethane were used over a 10-month period. The patient regained menstrual cyclicity, and clinical and biochemical hyperandrogenism normalized. This report underscores the need for an integrative approach to the management of multifactorial disorders such as PCOS and highlights the basic science and clinical data supporting the use of acupuncture, Vitex agnus-castus, and diindolylmethane in patients with this condition.
Copyright © 2019 InnoVision Professional Media Inc.

Entities:  

Year:  2019        PMID: 32549844      PMCID: PMC7219449     

Source DB:  PubMed          Journal:  Integr Med (Encinitas)        ISSN: 1546-993X


  16 in total

1.  [The efficacy of the complex medication Phyto-Hypophyson L in female, hormone-related sterility. A randomized, placebo-controlled clinical double-blind study].

Authors:  J Bergmann; B Luft; S Boehmann; B Runnebaum; I Gerhard
Journal:  Forsch Komplementarmed Klass Naturheilkd       Date:  2000-08

2.  True and sham acupuncture produced similar frequency of ovulation and improved LH to FSH ratios in women with polycystic ovary syndrome.

Authors:  Lisa M Pastore; Christopher D Williams; Jeffrey Jenkins; James T Patrie
Journal:  J Clin Endocrinol Metab       Date:  2011-08-03       Impact factor: 5.958

Review 3.  Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion.

Authors:  D A Ehrmann; R B Barnes; R L Rosenfield
Journal:  Endocr Rev       Date:  1995-06       Impact factor: 19.871

4.  Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells.

Authors:  Hien T Le; Charlene M Schaldach; Gary L Firestone; Leonard F Bjeldanes
Journal:  J Biol Chem       Date:  2003-03-27       Impact factor: 5.157

5.  Mastodynon(R) bei weiblicher Sterilität.

Authors: 
Journal:  Forsch Komplementarmed       Date:  1998

6.  Effects of electro-acupuncture on anovulation in women with polycystic ovary syndrome.

Authors:  E Stener-Victorin; U Waldenström; U Tägnfors; T Lundeberg; G Lindstedt; P O Janson
Journal:  Acta Obstet Gynecol Scand       Date:  2000-03       Impact factor: 3.636

7.  Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruits growing in Egypt.

Authors:  N A Ibrahim; A S Shalaby; R S Farag; G S Elbaroty; S M Nofal; E M Hassan
Journal:  Nat Prod Res       Date:  2008-04-15       Impact factor: 2.861

Review 8.  AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ANDROGEN EXCESS AND PCOS SOCIETY DISEASE STATE CLINICAL REVIEW: GUIDE TO THE BEST PRACTICES IN THE EVALUATION AND TREATMENT OF POLYCYSTIC OVARY SYNDROME - PART 2.

Authors:  Neil F Goodman; Rhoda H Cobin; Walter Futterweit; Jennifer S Glueck; Richard S Legro; Enrico Carmina
Journal:  Endocr Pract       Date:  2015-12       Impact factor: 3.443

9.  Screening of synthetic and plant-derived compounds for (anti)estrogenic and (anti)androgenic activities.

Authors:  Toine F H Bovee; Willem G E J Schoonen; Astrid R M Hamers; Marta Jorge Bento; Ad A C M Peijnenburg
Journal:  Anal Bioanal Chem       Date:  2008-01-11       Impact factor: 4.142

Review 10.  Polycystic ovary syndrome: effect and mechanisms of acupuncture for ovulation induction.

Authors:  Julia Johansson; Elisabet Stener-Victorin
Journal:  Evid Based Complement Alternat Med       Date:  2013-09-02       Impact factor: 2.629

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