Laetitia Bodet-Contentin1,2, Stephan Ehrmann3,4. 1. INSERM 1415 Center of Clinical Investigation, Department of Intensive Care Medicine, Tours University Hospital, Tours, France. 2. INSERM UMR 1246, University of Tours, Tours, France. 3. INSERM 1415 Center of Clinical Investigation, Department of Intensive Care Medicine, Tours University Hospital, Tours, France - stephanehrmann@gmail.com. 4. INSERM U1100, Center for the Study of Respiratory Diseases, University of Tours, Tours, France.