Literature DB >> 32548635

Performance of oropharyngeal swab testing compared to nasopharyngeal swab testing for diagnosis of COVID-19 -United States, January-February 2020.

Monita R Patel1, Darin Carroll1, Emily Ussery1, Hilary Whitham1, Christopher A Elkins1, Judith Noble-Wang1, James Kamile Rasheed1, Xioayan Lu1, Stephen Lindstrom1, Virginia Bowen1, Jessica Waller1, Gregory Armstrong1, Susan Gerber1, John T Brooks1.   

Abstract

Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days since illness onset, CDC real-time RT-PCR SARS-CoV-2 assay diagnostic results were 95.2% concordant. However, NP swab Ct values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect amount of SARS-CoV-2. Published by Oxford University Press for the Infectious Diseases Society of America 2020. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Keywords:  SARS-CoV-2; coronavirus; cycle threshold values; nasopharyngeal; oropharyngeal; testing

Year:  2020        PMID： 32548635      PMCID： PMC7337670          DOI： 10.1093/cid/ciaa759

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  4 in total

1.  Identification of respiratory viruses in adults: nasopharyngeal versus oropharyngeal sampling.

Authors:  David Lieberman; Devora Lieberman; Avi Shimoni; Ayelet Keren-Naus; Rachel Steinberg; Yonat Shemer-Avni
Journal:  J Clin Microbiol       Date:  2009-09-02       Impact factor: 5.948

2.  Virological assessment of hospitalized patients with COVID-2019.

Authors:  Roman Wölfel; Victor M Corman; Wolfgang Guggemos; Michael Seilmaier; Sabine Zange; Marcel A Müller; Daniela Niemeyer; Terry C Jones; Patrick Vollmar; Camilla Rothe; Michael Hoelscher; Tobias Bleicker; Sebastian Brünink; Julia Schneider; Rosina Ehmann; Katrin Zwirglmaier; Christian Drosten; Clemens Wendtner
Journal:  Nature       Date:  2020-04-01       Impact factor: 49.962

3.  Comparison of nasopharyngeal and oropharyngeal swabs for the diagnosis of eight respiratory viruses by real-time reverse transcription-PCR assays.

Authors:  Curi Kim; Jamal A Ahmed; Rachel B Eidex; Raymond Nyoka; Lilian W Waiboci; Dean Erdman; Adan Tepo; Abdirahman S Mahamud; Wamburu Kabura; Margaret Nguhi; Philip Muthoka; Wagacha Burton; Robert F Breiman; M Kariuki Njenga; Mark A Katz
Journal:  PLoS One       Date:  2011-06-30       Impact factor: 3.240

4.  SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients.

Authors:  Lirong Zou; Feng Ruan; Mingxing Huang; Lijun Liang; Huitao Huang; Zhongsi Hong; Jianxiang Yu; Min Kang; Yingchao Song; Jinyu Xia; Qianfang Guo; Tie Song; Jianfeng He; Hui-Ling Yen; Malik Peiris; Jie Wu
Journal:  N Engl J Med       Date:  2020-02-19       Impact factor: 91.245
  4 in total

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