Faryal Khamis1, Ibrahim Al-Zakwani2, Hamed Al Naamani3, Sultan Al Lawati4, Nenad Pandak3, Muna Ba Omar5, Maher Al Bahrani6, Zakaryia Al Bulushi3, Huda Al Khalili6, Issa Al Salmi7, Ruwaida Al Ismaili4, Salah T Al Awaidy8. 1. Adult Infectious Diseases, Department of Medicine, Royal Hospital, Ministry of Health, Muscat Oman. Electronic address: khami001@gmail.com. 2. Department of Pharmacology & Clinical Pharmacy, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman. 3. Adult Infectious Diseases, Department of Medicine, Royal Hospital, Ministry of Health, Muscat Oman. 4. Department of Medicine, Al Nahdha Hospital, Ministry of Health, Muscat, Oman. 5. Oman Medical Speciality Board, Muscat, Oman. 6. Department of Anaesthesia and Critical Care e, Royal Hospital, Ministry of Health, Muscat Oman. 7. Department of Nephrology, Royal Hospital, Ministry of Health, Muscat, Oman. 8. Department of Anaesthesia and Critical Care e, Royal Hospital, Ministry of Health, Muscat Oman. Electronic address: salah.awaidy@gmail.com.
Abstract
INTRODUCTION: To identify the clinical characteristics and outcomes of hospitalized patients with COVID-19 in Oman. METHODS: A case series of hospitalized COVID-19 laboratory-confirmed patients between February 24th through April 24th, 2020, from two hospitals in Oman. Analyses were performed using univariate statistics. RESULTS: The cohort included 63 patients with an overall mean age of 48±16 years and 84% (n=53) were males. A total of 38% (n=24) of the hospitalized patients were admitted to intensive care unit (ICU). Fifty one percent (n=32) of patients had at least one co-morbidity with diabetes mellitus (DM) (32%; n=20) and hypertension (32%; n=20) as the most common co-morbidities followed by chronic heart and renal diseases (12.8%; n=8). The most common presenting symptoms at onset of illness were fever (84%; n=53), cough (75%; n=47) and shortness of breaths (59%; n=37). All except two patients (97%; n=61) were treated with either chloroquine or hydroxychloroquine, while the three most prescribed antibiotics were ceftriaxone (79%; n=50), azithromycin (71%; n=45), and the piperacillin/tazobactam combination (49%; n=31). A total of 59% (n=37), 49% (n=31) and 24% (n=15) of the patients were on lopinavir/ritonavir, interferons, or steroids, respectively. Mortality was documented in (8%; n=5) of the patients while 68% (n=43) of the study cohort recovered. Mortality was associated with those that were admitted to ICU (19% vs 0; p=0.009), mechanically ventilated (31% vs 0; p=0.001), had DM (20% vs 2.3%; p=0.032), older (62 vs 47 years; p=0.045), had high total bilirubin (43% vs 2.3%; p=0.007) and those with high C-reactive protein (186 vs 90mg/dL; p=0.009) and low corrected calcium (15% vs 0%; p=0.047). CONCLUSIONS: ICU admission, those on mechanical ventilation, the elderly, those with high total bilirubin and low corrected calcium were associated with high mortality in hospitalized COVID-19 patients.
INTRODUCTION: To identify the clinical characteristics and outcomes of hospitalized patients with COVID-19 in Oman. METHODS: A case series of hospitalized COVID-19 laboratory-confirmed patients between February 24th through April 24th, 2020, from two hospitals in Oman. Analyses were performed using univariate statistics. RESULTS: The cohort included 63 patients with an overall mean age of 48±16 years and 84% (n=53) were males. A total of 38% (n=24) of the hospitalized patients were admitted to intensive care unit (ICU). Fifty one percent (n=32) of patients had at least one co-morbidity with diabetes mellitus (DM) (32%; n=20) and hypertension (32%; n=20) as the most common co-morbidities followed by chronic heart and renal diseases (12.8%; n=8). The most common presenting symptoms at onset of illness were fever (84%; n=53), cough (75%; n=47) and shortness of breaths (59%; n=37). All except two patients (97%; n=61) were treated with either chloroquine or hydroxychloroquine, while the three most prescribed antibiotics were ceftriaxone (79%; n=50), azithromycin (71%; n=45), and the piperacillin/tazobactam combination (49%; n=31). A total of 59% (n=37), 49% (n=31) and 24% (n=15) of the patients were on lopinavir/ritonavir, interferons, or steroids, respectively. Mortality was documented in (8%; n=5) of the patients while 68% (n=43) of the study cohort recovered. Mortality was associated with those that were admitted to ICU (19% vs 0; p=0.009), mechanically ventilated (31% vs 0; p=0.001), had DM (20% vs 2.3%; p=0.032), older (62 vs 47 years; p=0.045), had high total bilirubin (43% vs 2.3%; p=0.007) and those with high C-reactive protein (186 vs 90mg/dL; p=0.009) and low corrected calcium (15% vs 0%; p=0.047). CONCLUSIONS: ICU admission, those on mechanical ventilation, the elderly, those with high total bilirubin and low corrected calcium were associated with high mortality in hospitalized COVID-19patients.
Authors: Saad Alhumaid; Abbas Al Mutair; Zainab Al Alawi; Khulud Al Salman; Nourah Al Dossary; Ahmed Omar; Mossa Alismail; Ali M Al Ghazal; Mahdi Bu Jubarah; Hanan Al Shaikh; Maher M Al Mahdi; Sarah Y Alsabati; Dayas K Philip; Mohammed Y Alyousef; Abdulsatar H Al Brahim; Maitham S Al Athan; Salamah A Alomran; Hatim S Ahmed; Haifa Al-Shammari; Alyaa Elhazmi; Ali A Rabaan; Jaffar A Al-Tawfiq; Awad Al-Omari Journal: Eur J Med Res Date: 2021-05-24 Impact factor: 2.175
Authors: Ibrahim Y Hachim; Mahmood Y Hachim; Kashif Bin Naeem; Haifa Hannawi; Issa Al Salmi; Ibrahim Al-Zakwani; Suad Hannawi Journal: Oman Med J Date: 2021-02-07
Authors: Shaher M Samrah; Abdel-Hameed W Al-Mistarehi; Ali M Ibnian; Liqaa A Raffee; Suleiman M Momany; Musa Al-Ali; Wail A Hayajneh; Dawood H Yusef; Samah M Awad; Basheer Y Khassawneh Journal: Ann Med Surg (Lond) Date: 2020-07-18