Literature DB >> 32543703

SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure.

Alain R Thierry1, Benoit Roch2.   

Abstract

We demonstrate that the general clinical conditions, risk factors and numerous pathological and biological features of COVID-19 are analogous with various disorders caused by the uncontrolled formation of neutrophil extracellular traps and their by-products. Given the rapid evolution of this disease's symptoms and its lethality, we hypothesize that SARS-CoV2 evades innate immune response causing COVID-19 progresses under just such an amplifier loop, leading to a massive, uncontrolled inflammation process. This work allows us to propose new strategies for treating the pandemic.
© 2020 The Author(s).

Entities:  

Keywords:  COVID19; Neutrophil; Traps; circulating DNA; pathogenesis

Mesh:

Substances:

Year:  2020        PMID: 32543703     DOI: 10.1042/CS20200531

Source DB:  PubMed          Journal:  Clin Sci (Lond)        ISSN: 0143-5221            Impact factor:   6.124


  19 in total

1.  Casting a wide NET: an update on uncontrolled NETosis in response to COVID-19 infection.

Authors:  Erin B Taylor
Journal:  Clin Sci (Lond)       Date:  2022-07-15       Impact factor: 6.876

2.  Host/genetic factors associated with COVID-19 call for precision medicine.

Authors:  Alain R Thierry
Journal:  Precis Clin Med       Date:  2020-07-21

3.  Cell-free DNA in plasma as an essential immune system regulator.

Authors:  M Korabecna; A Zinkova; I Brynychova; B Chylikova; P Prikryl; L Sedova; P Neuzil; O Seda
Journal:  Sci Rep       Date:  2020-10-15       Impact factor: 4.379

Review 4.  COVID-19: Current knowledge in clinical features, immunological responses, and vaccine development.

Authors:  Ramandeep Singh; Alisha Kang; Xiangqian Luo; Mangalakumari Jeyanathan; Amy Gillgrass; Sam Afkhami; Zhou Xing
Journal:  FASEB J       Date:  2021-03       Impact factor: 5.834

5.  Vasculitis and Neutrophil Extracellular Traps in Lungs of Golden Syrian Hamsters With SARS-CoV-2.

Authors:  Kathrin Becker; Georg Beythien; Nicole de Buhr; Stephanie Stanelle-Bertram; Berfin Tuku; Nancy Mounogou Kouassi; Sebastian Beck; Martin Zickler; Lisa Allnoch; Gülsah Gabriel; Maren von Köckritz-Blickwede; Wolfgang Baumgärtner
Journal:  Front Immunol       Date:  2021-04-12       Impact factor: 7.561

6.  Advocacy of targeting protease-activated receptors in severe coronavirus disease 2019.

Authors:  Saravanan Subramaniam; Wolfram Ruf; Markus Bosmann
Journal:  Br J Pharmacol       Date:  2021-07-07       Impact factor: 8.739

Review 7.  Neutrophil Extracellular Traps and By-Products Play a Key Role in COVID-19: Pathogenesis, Risk Factors, and Therapy.

Authors:  Alain R Thierry; Benoit Roch
Journal:  J Clin Med       Date:  2020-09-11       Impact factor: 4.241

8.  Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19.

Authors:  Coraline Radermecker; Nancy Detrembleur; Julien Guiot; Etienne Cavalier; Monique Henket; Céline d'Emal; Céline Vanwinge; Didier Cataldo; Cécile Oury; Philippe Delvenne; Thomas Marichal
Journal:  J Exp Med       Date:  2020-12-07       Impact factor: 14.307

9.  How NETosis could drive "Post-COVID-19 syndrome" among survivors.

Authors:  Serge A Sawadogo; Bonnie Dighero-Kemp; Dieu-Donné Ouédraogo; Lisa Hensley; Jean Sakandé
Journal:  Immunol Lett       Date:  2020-09-29       Impact factor: 3.685

10.  Longitudinal prediction of hospital-acquired acute kidney injury in COVID-19: a two-center study.

Authors:  Justin Y Lu; Wei Hou; Tim Q Duong
Journal:  Infection       Date:  2021-06-26       Impact factor: 7.455

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