Literature DB >> 32543288

What is the potential of neurostimulation in the treatment of motor symptoms in schizophrenia?

Stephanie Lefebvre1, Anastasia Pavlidou1, Sebastian Walther1.   

Abstract

INTRODUCTION: Motor abnormalities in schizophrenia are frequent and linked to poor social functioning and low quality of life. To date, there are no effective treatments available to alleviate these motor impairments. Previous studies have linked altered connections within the cerebral motor circuits to motor abnormalities. AREAS COVERED: This perspective article will discuss the efficacy of noninvasive brain stimulation (NIBS) techniques as a potential therapeutic tool in improving motor impairments in schizophrenia. EXPERT OPINION: The cortical motor network is easily accessible using NIBS, which has been proven reliable in restoring motor functioning across different pathologies. It is important to establish protocols that explore optimal treatment targets, timing, and duration of the stimulation, as well as, the standardization of motor assessments in order to compare across different brain stimulation methodologies. The authors believe NIBS to be ideal in restoring and improving motor impairments in schizophrenia.

Entities:  

Keywords:  NIBS; Schizophrenia; motor abnornalities; motor circuit; therapeutic intervention

Mesh:

Year:  2020        PMID: 32543288     DOI: 10.1080/14737175.2020.1775586

Source DB:  PubMed          Journal:  Expert Rev Neurother        ISSN: 1473-7175            Impact factor:   4.618


  11 in total

1.  Non-invasive brain stimulation: the next frontier in psychiatry.

Authors:  Sebastian Walther; Chris Baeken
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2021-01-12       Impact factor: 5.270

2.  Nonverbal communication remains untouched: No beneficial effect of symptomatic improvement on poor gesture performance in schizophrenia.

Authors:  Florian Wüthrich; Anastasia Pavlidou; Katharina Stegmayer; Sarah Eisenhardt; Jeanne Moor; Lea Schäppi; Tim Vanbellingen; Stephan Bohlhalter; Sebastian Walther
Journal:  Schizophr Res       Date:  2020-09-01       Impact factor: 4.939

3.  Low physical activity is associated with two hypokinetic motor abnormalities in psychosis.

Authors:  Sebastian Walther; Irena Vladimirova; Danai Alexaki; Lea Schäppi; Kathrine S F Damme; Vijay A Mittal; Stewart A Shankman; Katharina Stegmayer
Journal:  J Psychiatr Res       Date:  2021-11-08       Impact factor: 4.791

4.  Motor Behavior is Relevant for Understanding Mechanism, Bolstering Prediction, And Improving Treatment: A Transdiagnostic Perspective.

Authors:  Sebastian Walther; Vijay A Mittal
Journal:  Schizophr Bull       Date:  2022-06-21       Impact factor: 7.348

5.  Using Virtual Reality as a Tool in the Rehabilitation of Movement Abnormalities in Schizophrenia.

Authors:  Anastasia Pavlidou; Sebastian Walther
Journal:  Front Psychol       Date:  2021-01-07

6.  Potential Locations for Non-Invasive Brain Stimulation in Treating Schizophrenia: A Resting-State Functional Connectivity Analysis.

Authors:  Yanzhe Ning; Sisi Zheng; Sitong Feng; Binlong Zhang; Hongxiao Jia
Journal:  Front Neurol       Date:  2021-12-15       Impact factor: 4.003

7.  Using dynamic point light display stimuli to assess gesture deficits in schizophrenia.

Authors:  Anastasia Pavlidou; Victoria Chapellier; Lydia Maderthaner; Sofie von Känel; Sebastian Walther
Journal:  Schizophr Res Cogn       Date:  2022-02-03

8.  Brain Stimulation and Group Therapy to Improve Gesture and Social Skills in Schizophrenia-The Study Protocol of a Randomized, Sham-Controlled, Three-Arm, Double-Blind Trial.

Authors:  Victoria Chapellier; Anastasia Pavlidou; Daniel R Mueller; Sebastian Walther
Journal:  Front Psychiatry       Date:  2022-07-07       Impact factor: 5.435

9.  Measuring catatonia motor behavior with objective instrumentation.

Authors:  Sofie von Känel; Niluja Nadesalingam; Danai Alexaki; Daniel Baumann Gama; Alexandra Kyrou; Stéphanie Lefebvre; Sebastian Walther
Journal:  Front Psychiatry       Date:  2022-08-17       Impact factor: 5.435

10.  Hand gesture performance is impaired in major depressive disorder: A matter of working memory performance?

Authors:  Anastasia Pavlidou; Petra V Viher; Hanta Bachofner; Florian Weiss; Katharina Stegmayer; Stewart A Shankman; Vijay A Mittal; Sebastian Walther
Journal:  J Affect Disord       Date:  2021-05-28       Impact factor: 6.533

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