Literature DB >> 32542946

Do facemasks protect against COVID-19?

David Isaacs1,2,3,4, Philip Britton1,2,3,4, Annaleise Howard-Jones1,2, Alison Kesson1,2, Ameneh Khatami1,4, Ben Marais1,4, Claire Nayda1,2, Alexander Outhred1,2.   

Abstract

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Year:  2020        PMID: 32542946      PMCID: PMC7323223          DOI: 10.1111/jpc.14936

Source DB:  PubMed          Journal:  J Paediatr Child Health        ISSN: 1034-4810            Impact factor:   1.954


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Respiratory viruses like coronaviruses and influenza infect us through inhaling droplets or by touching contaminated surfaces then rubbing our nose, mouth or eyes. Virus can spread further in an aerosol if an infected patient is subjected to an aerosol‐generating procedure such as a nebuliser or mechanical ventilation. There are two major classes of facemask: medical/surgical masks are loose‐fitting, disposable masks that filter out droplets, while tight‐fitting N95 or P2 respirator masks are designed to be more effective filters of airborne particles. N95/P2 masks are more expensive. Both surgical and N95 masks may become a scarce resource. Evidence on the efficacy of masks is confounded by whether or not they are being used in a pandemic; whether by health‐care workers or the public, and by the concomitant use of hand‐washing, social distancing and other personal protective equipment. A meta‐analysis of randomised controlled trials of pre‐COVID‐19 showed that surgical masks or N95 respirators reduced clinical respiratory illness in health‐care workers by 41% and influenza‐like illness by 66%: they work but are far from perfect. N95 masks were not statistically better than surgical masks in preventing proven influenza, nor in preventing COVID‐19, although the latter is based on weak data. N95 masks are more efficient filters of small particles, but these findings suggest it is reasonable to recommend that health‐care workers use surgical masks when there is risk of droplet spread and reserve precious N95 masks for health‐care workers performing aerosol‐generating procedures. Some health‐care and ancillary hospital staff have mooted wearing surgical facemasks all the time even when asymptomatic to protect themselves and patients. However, given the current low and declining transmission within the Australian community, the risk of a health worker inadvertently catching or spreading the infection if not wearing a mask is very low. Symptomatic health‐care workers should not return to work until they have been tested and found to be negative for COVID‐19. The public might wear masks to avoid infection or to protect others. During the 2009 pandemic of H1N1 influenza (swine flu), encouraging the public to wash their hands reduced the incidence of infection significantly whereas wearing facemasks did not. There is no good evidence that facemasks protect the public against infection with respiratory viruses, including COVID‐19. However, absence of proof of an effect is not the same as proof of absence of an effect. During the pandemics caused by swine flu and by the coronaviruses which caused SARS and MERS, many people in Asia and elsewhere walked around wearing surgical or homemade cotton masks to protect themselves. One danger of doing this is the illusion of protection. Surgical facemasks are designed to be discarded after single use. As they become moist they become porous and no longer protect. Indeed, experiments have shown that surgical and cotton masks do not trap the SARS‐CoV‐2 (COVID‐19) virus, which can be detected on the outer surface of the masks for up to 7 days. , Thus, a pre‐symptomatic or mildly infected person wearing a facemask for hours without changing it and without washing hands every time they touched the mask could paradoxically increase the risk of infecting others. Because the USA is in a desperate situation, their Centers for Disease Control has recommended the public wear homemade cloth masks. This was essentially done in an effort to try and reduce community transmission, especially from people who may not perceive themselves to be symptomatic, rather than to protect the wearer, although the evidence for this is scant. In contrast, the World Health Organization currently recommends against the public routinely wearing facemasks. In Australia and New Zealand currently, the questionable benefits arguably do not justify health‐care staff wearing surgical masks when treating low‐risk patients and may impede the normal caring relationship between patients, parents and staff. We counsel against such practice, at least at present.
  7 in total

Review 1.  Effectiveness of personal protective measures in reducing pandemic influenza transmission: A systematic review and meta-analysis.

Authors:  Patrick Saunders-Hastings; James A G Crispo; Lindsey Sikora; Daniel Krewski
Journal:  Epidemics       Date:  2017-04-30       Impact factor: 4.396

2.  Universal Masking in Hospitals in the Covid-19 Era.

Authors:  Michael Klompas; Charles A Morris; Julia Sinclair; Madelyn Pearson; Erica S Shenoy
Journal:  N Engl J Med       Date:  2020-04-01       Impact factor: 91.245

Review 3.  Effectiveness of Masks and Respirators Against Respiratory Infections in Healthcare Workers: A Systematic Review and Meta-Analysis.

Authors:  Vittoria Offeddu; Chee Fu Yung; Mabel Sheau Fong Low; Clarence C Tam
Journal:  Clin Infect Dis       Date:  2017-11-13       Impact factor: 9.079

4.  Effectiveness of N95 respirators versus surgical masks against influenza: A systematic review and meta-analysis.

Authors:  Youlin Long; Tengyue Hu; Liqin Liu; Rui Chen; Qiong Guo; Liu Yang; Yifan Cheng; Jin Huang; Liang Du
Journal:  J Evid Based Med       Date:  2020-03-13

5.  Effectiveness of Surgical and Cotton Masks in Blocking SARS-CoV-2: A Controlled Comparison in 4 Patients.

Authors:  Seongman Bae; Min-Chul Kim; Ji Yeun Kim; Hye-Hee Cha; Joon Seo Lim; Jiwon Jung; Min-Jae Kim; Dong Kyu Oh; Mi-Kyung Lee; Seong-Ho Choi; Minki Sung; Sang-Bum Hong; Jin-Won Chung; Sung-Han Kim
Journal:  Ann Intern Med       Date:  2020-04-06       Impact factor: 25.391

6.  Medical masks vs N95 respirators for preventing COVID-19 in healthcare workers: A systematic review and meta-analysis of randomized trials.

Authors:  Jessica J Bartoszko; Mohammed Abdul Malik Farooqi; Waleed Alhazzani; Mark Loeb
Journal:  Influenza Other Respir Viruses       Date:  2020-04-21       Impact factor: 4.380

7.  Rational use of face masks in the COVID-19 pandemic.

Authors:  Shuo Feng; Chen Shen; Nan Xia; Wei Song; Mengzhen Fan; Benjamin J Cowling
Journal:  Lancet Respir Med       Date:  2020-03-20       Impact factor: 30.700

  7 in total
  7 in total

Review 1.  Retracted: Facemasks in the COVID-19 era: A health hypothesis.

Authors:  Baruch Vainshelboim
Journal:  Med Hypotheses       Date:  2020-11-22       Impact factor: 1.538

2.  Health Risks, Preventive Behaviours and Respiratory Illnesses at the 2019 Arbaeen: Implications for COVID-19 and Other Pandemics.

Authors:  Farah Al-Ansari; Masoud Mirzaei; Basma Al-Ansari; Mohammad Basim Al-Ansari; Mohammed Saeed Abdulzahra; Harunor Rashid; Grant A Hill-Cawthorne; Mustafa Al Ansari; Joel Negin; Katherine Conigrave
Journal:  Int J Environ Res Public Health       Date:  2021-03-22       Impact factor: 3.390

Review 3.  Face masks against COVID-19: Standards, efficacy, testing and decontamination methods.

Authors:  Jerry T J Ju; Leah N Boisvert; Yi Y Zuo
Journal:  Adv Colloid Interface Sci       Date:  2021-04-29       Impact factor: 12.984

4.  Behavioral drivers and observation of face covering use during the COVID-19 pandemic among outpatients and visitors at a tertiary hospital in Thailand.

Authors:  Nanta Kliangkird; Sommanas Naknual; Tippawan Liabsuetrakul; Wit Wichaidit
Journal:  J Educ Health Promot       Date:  2021-11-30

5.  Effect of facemasks on the tear film during the COVID-19 pandemic.

Authors:  Hisham Samy Shalaby; Marwa Ebrahim ElSebaay Eldesouky
Journal:  Eur J Ophthalmol       Date:  2022-06-22       Impact factor: 1.922

6.  Apocalypse perhaps.

Authors:  David Isaacs
Journal:  J Paediatr Child Health       Date:  2020-08       Impact factor: 1.954

7.  Facemask against viral respiratory infections among Hajj pilgrims: A challenging cluster-randomized trial.

Authors:  Mohammad Alfelali; Elizabeth A Haworth; Osamah Barasheed; Al-Mamoon Badahdah; Hamid Bokhary; Mohamed Tashani; Mohammad I Azeem; Jen Kok; Janette Taylor; Elizabeth H Barnes; Haitham El Bashir; Gulam Khandaker; Edward C Holmes; Dominic E Dwyer; Leon G Heron; Godwin J Wilson; Robert Booy; Harunor Rashid
Journal:  PLoS One       Date:  2020-10-13       Impact factor: 3.240

  7 in total

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