| Literature DB >> 32539418 |
Tengfei Yao1, Fang Zhang1, Junliang Zhang2, Lu Liu1,3.
Abstract
Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.Entities:
Year: 2020 PMID: 32539418 DOI: 10.1021/acs.orglett.0c01643
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005