Literature DB >> 32535881

Therapeutic implications of the PP2A/MET signalling axis in doxorubicin-induced cardiotoxicity and antitumour properties.

Ion Cristóbal1,2, Jaime Rubio1,2, Andrea Santos1,2, Melani Luque3, Marta Sanz-Alvarez3, Federico Rojo3, Jesús García-Foncillas1,2.   

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Year:  2020        PMID： 32535881      PMCID： PMC7393192          DOI： 10.1111/bph.15130

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


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  5 in total

1.  Regulation of angiotensin II-induced phosphorylation of STAT3 in vascular smooth muscle cells.

Authors:  H Liang; V J Venema; X Wang; H Ju; R C Venema; M B Marrero
Journal:  J Biol Chem       Date:  1999-07-09       Impact factor: 5.157

2.  Bi-directional regulation of Ser-985 phosphorylation of c-met via protein kinase C and protein phosphatase 2A involves c-Met activation and cellular responsiveness to hepatocyte growth factor.

Authors:  Atsuko Hashigasako; Mitsuru Machide; Takahiro Nakamura; Kunio Matsumoto; Toshikazu Nakamura
Journal:  J Biol Chem       Date:  2004-04-09       Impact factor: 5.157

Review 3.  Multiple pathways regulated by the tumor suppressor PP2A in transformation.

Authors:  Jukka Westermarck; William C Hahn
Journal:  Trends Mol Med       Date:  2008-03-10       Impact factor: 11.951

4.  PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects.

Authors:  Raúl Rincón; Ion Cristóbal; Sandra Zazo; Oriol Arpí; Silvia Menéndez; Rebeca Manso; Ana Lluch; Pilar Eroles; Ana Rovira; Joan Albanell; Jesús García-Foncillas; Juan Madoz-Gúrpide; Federico Rojo
Journal:  Oncotarget       Date:  2015-02-28

5.  Activation of the MET receptor attenuates doxorubicin-induced cardiotoxicity in vivo and in vitro.

Authors:  Simona Gallo; Martina Spilinga; Raffaella Albano; Giuseppe Ferrauto; Enza Di Gregorio; Elena Casanova; Davide Balmativola; Alessandro Bonzano; Carla Boccaccio; Anna Sapino; Paolo Maria Comoglio; Tiziana Crepaldi
Journal:  Br J Pharmacol       Date:  2020-05-29       Impact factor: 8.739
  5 in total

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