Leptomeningeal involvement in a patient with systemic lupus erythematosus infected by COVID-19.

Magnetic resonance (MR) imaging showing a few leptomeningeal micronodular lesions (Fig. 1 ). A 43-year-old woman was referred with complaints of severe headache, cough, and fever. The patient had systemic lupus erythematosus disease for ten years. Her body temperature was measured as 38.6 °C. Laboratory findings revealed mild leukocytosis (WBC = 12,450/mm3). Real-time reverse-transcriptase-polymerase chain reaction (rRT-PCR) was positive for COVID-19. Thorax computed tomography (CT) showed common ground glass densities in both lung parenchyma. Magnetic resonance (MR) imaging showed a few leptomeningeal micronodular lesions (Fig. 1). The lupus patients may be more susceptible for a more severe COVID-19 disease course [1]. CT scans appear sensitive virus detection [2].

Fig. 1