Literature DB >> 32533153

Behavioral Screening of Alcohol Effects and Individual Differences in Zebrafish (Danio rerio).

Heloysa Araujo-Silva1, Maria Elisa Leite-Ferreira1, Ana Carolina Luchiari1.   

Abstract

AIM: To better understand the individual differences that make up a population, this study aimed to evaluate the effects of different alcoholic concentrations on the behavioral profiles of zebrafish (Danio rerio).
METHODS: For this purpose, adult animals were separated into two behavioral profiles: bold and shy, according to the emergence order. Bold and shy fish were individually tested for exploration after exposure to the drug. Acute exposure treatments were alcohol 0.00, 0.10, 0.25 and 0.50%. The behavioral parameters evaluated were speed while moving, maximum speed, total distance traveled and distance from the bottom of the tank.
RESULTS: For the groups that did not receive alcohol, bold animals showed higher speed while moving. Shy 0.00% and shy 0.10% had the highest maximum speed compared with other concentrations and profiles. For the distance from the bottom tank, our results showed that the increase induced by the low acute dose (0.10%) was observed for both profiles.
CONCLUSIONS: Our results corroborate with previous findings that alcohol affects the behavioral profiles of zebrafish differently, with bold animals apparently more resistant to these changes.
© The Author(s) 2020. Medical Council on Alcohol and Oxford University Press. All rights reserved.

Entities:  

Year:  2020        PMID: 32533153     DOI: 10.1093/alcalc/agaa046

Source DB:  PubMed          Journal:  Alcohol Alcohol        ISSN: 0735-0414            Impact factor:   2.826


  3 in total

1.  The importance of individual variation for the interpretation of behavioural studies: ethanol effects vary with basal activity level in zebrafish larvae.

Authors:  Raissa Davis; Floris Luchtenburg; Michael Richardson; Marcel Schaaf; Christian Tudorache; Hans Slabbekoorn
Journal:  Psychopharmacology (Berl)       Date:  2021-09-11       Impact factor: 4.415

2.  Differences in the Alcohol Preference Assessment of Shy and Bold Zebrafish.

Authors:  Marina Sanson Bellot; Isabela Inforzato Guermandi; Bruno Camargo-Dos-Santos; Percília Cardoso Giaquinto
Journal:  Front Behav Neurosci       Date:  2022-02-24       Impact factor: 3.558

3.  Differential effects of ethanol on behavior and GABAA receptor expression in adult zebrafish (Danio rerio) with alternative stress coping styles.

Authors:  Alexander C Goodman; Ryan Y Wong
Journal:  Sci Rep       Date:  2020-08-04       Impact factor: 4.379

  3 in total

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