Literature DB >> 32531434

Molecular basis of macrolide-lincosamide-streptogramin (MLS) resistance in Finegoldia magna clinical isolates.

François Guérin1, Sabrine Lachaal2, Michel Auzou1, Cécile Le Brun3, Olivier Barraud4, Jean-Winoc Decousser5, Reto Lienhard6, Régine Baraduc7, Luc Dubreuil8, Vincent Cattoir9.   

Abstract

Of 69 clinical isolates of Finegoldia magna tested, 36% presented high-level MICs of erythromycin (>256 μg/ml), harboring erm(A) (n = 20) or erm(B) (n=5). Of nine isolates exhibiting an inducible resistance phenotype to macrolides-lincosamides-streptogramins B, four (44%) were susceptible with a potential risk of treatment failure due to emergence of resistant mutants.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  F. magna; GPAC; MLS; anaerobes; clindamycin; erm(A); erm(B)

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Year:  2020        PMID: 32531434     DOI: 10.1016/j.anaerobe.2020.102220

Source DB:  PubMed          Journal:  Anaerobe        ISSN: 1075-9964            Impact factor:   3.331


  2 in total

Review 1.  Antibiotic Resistance and Mechanisms of Pathogenic Bacteria in Tubo-Ovarian Abscess.

Authors:  Huanna Tang; Hui Zhou; Runju Zhang
Journal:  Front Cell Infect Microbiol       Date:  2022-07-27       Impact factor: 6.073

2.  Analysis of Urinary Flora Characteristics in Urinary Tumor Based on 16S rRNA Sequence.

Authors:  Jin Qiu; Jianxin Liu; Yi Zhong; Wang Liu; Zhangjie Zhou; Yun Li; Shiying Li
Journal:  Biomed Res Int       Date:  2022-07-14       Impact factor: 3.246

  2 in total

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