| Literature DB >> 32531270 |
Ihsan Ekin Demir1, Carmen Mota Reyes2, Wasfi Alrawashdeh3, Güralp O Ceyhan4, Sylvie Deborde5, Helmut Friess2, Kivanc Görgülü6, Rouzanna Istvanffy2, David Jungwirth2, Rohini Kuner7, Maria Maryanovich8, Shorook Na'ara9, Simon Renders10, Jami L Saloman11, Nicole N Scheff12, Hendrik Steenfadt2, Pavel Stupakov2, Vera Thiel10, Divij Verma8, Bengi Su Yilmaz2, Ruth A White13, Timothy C Wang14, Richard J Wong5, Paul S Frenette15, Ziv Gil9, Brian M Davis16.
Abstract
Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic.Entities:
Year: 2020 PMID： 32531270 DOI： 10.1016/j.ccell.2020.05.023
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743