Literature DB >> 32530028

Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome.

David H Abbott1, Jon E Levine2, Daniel A Dumesic3.   

Abstract

Entities:  

Keywords:  androgen receptor knockout; brown adipocyte; hyperandrogenism; macrophage; neuron; white adipocyte

Mesh：

Substances：

Year:  2020        PMID： 32530028      PMCID： PMC7446857          DOI： 10.1210/endocr/bqaa095

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


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  9 in total

1.  Polycystic ovarian syndrome: evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone.

Authors:  C A Eagleson; M B Gingrich; C L Pastor; T K Arora; C M Burt; W S Evans; J C Marshall
Journal:  J Clin Endocrinol Metab       Date:  2000-11       Impact factor: 5.958

Review 2.  Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome.

Authors:  Elisabet Stener-Victorin; Vasantha Padmanabhan; Kirsty A Walters; Rebecca E Campbell; Anna Benrick; Paolo Giacobini; Daniel A Dumesic; David H Abbott
Journal:  Endocr Rev       Date:  2020-07-01       Impact factor: 19.871

3.  Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome.

Authors:  Aimee S L Caldwell; Melissa C Edwards; Reena Desai; Mark Jimenez; Robert B Gilchrist; David J Handelsman; Kirsty A Walters
Journal:  Proc Natl Acad Sci U S A       Date:  2017-03-20       Impact factor: 11.205

4.  Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice.

Authors:  Stanley Andrisse; Katelyn Billings; Ping Xue; Sheng Wu
Journal:  Am J Physiol Endocrinol Metab       Date:  2017-12-19       Impact factor: 4.310

5.  Androgen Action in Adipose Tissue and the Brain are Key Mediators in the Development of PCOS Traits in a Mouse Model.

Authors:  Madeleine J Cox; Melissa C Edwards; Valentina Rodriguez Paris; Ali Aflatounian; William L Ledger; Robert B Gilchrist; Vasantha Padmanabhan; David J Handelsman; Kirsty A Walters
Journal:  Endocrinology       Date:  2020-07-01       Impact factor: 4.736

6.  Adipose Insulin Resistance in Normal-Weight Women With Polycystic Ovary Syndrome.

Authors:  Daniel A Dumesic; Julia D Phan; Karen L Leung; Tristan R Grogan; Xiangmiang Ding; Xinmin Li; Luis R Hoyos; David H Abbott; Gregorio D Chazenbalk
Journal:  J Clin Endocrinol Metab       Date:  2019-06-01       Impact factor: 5.958

7.  Ovulatory effects of flutamide in the polycystic ovary syndrome.

Authors:  Roberto Paradisi; Raffaella Fabbri; Cesare Battaglia; Stefano Venturoli
Journal:  Gynecol Endocrinol       Date:  2013-01-18       Impact factor: 2.260

8.  Androgen signaling pathways driving reproductive and metabolic phenotypes in a PCOS mouse model.

Authors:  Ali Aflatounian; Melissa C Edwards; Valentina Rodriguez Paris; Michael J Bertoldo; Reena Desai; Robert B Gilchrist; William L Ledger; David J Handelsman; Kirsty A Walters
Journal:  J Endocrinol       Date:  2020-06       Impact factor: 4.286

Review 9.  Fast, furious and enduring: Sensitive versus critical periods in sexual differentiation of the brain.

Authors:  Margaret M McCarthy; Kevin Herold; Sara L Stockman
Journal:  Physiol Behav       Date:  2017-10-31
  9 in total

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