The caption submitted for Figure 1 was the same as the caption for Figure 2, and incorrect.The correct caption for Figure 1 is shown below.Hypothesised relationship between genetic variant G, modifiable exposure X and outcome Y in the presence of an unobserved confounder, denoted by U. The line from G to X represents instrumental variable assumption IV1. Dashed lines represent potential violations of the instrumental variable assumptions IV2 and IV3.
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