Reply "Role of antibiotic envelopes in preventing cardiac implantable electronic device infection: A meta-analysis of 14 859 procedures".

Sir,

We would like to thank Asbeutah, AAA for his interest in our manuscript and meaningful insight.1, 2 However even following exclusion of the study by Kay et al from the meta‐analysis (as the study did not report any true infections and the numbers reported were from a predictive model, combining results from other studies) the results and conclusion did not differ.3 Antibiotic envelope reduced the risk of cardiac implantable electronic device infections (RR: 0.51, CI: 0.37‐0.69, P < .05, I 2 = 66%, χ 2 P < .05) (Figure 1). Further as rightly pointed out, the absorbable envelope group of Kolek et al was not included in the analysis due to the overlap of subjects in the control group.4 This was to avoid the error of “double counting.”5

FIGURE 1

Forest plot for risk of infection (major/minor)

CONFLICT OF INTEREST

Authors declare no conflict of interests for this article.