Literature DB >> 32528195

Broad beans (Vicia faba) and the potential to protect from COVID-19 coronavirus infection.

Mutasim I Khalil1,2, Mustafa A Salih3,2, Ali A Mustafa4,2.   

Abstract

Due to its high linoleic acid concentration (41%), sesame oil has been proposed to have the potential to protect from COVID-19 coronavirus (SARS-CoV-2) infection, which was characterised by the World Health Organization as a pandemic in March 2020. Unsaturated fatty acids, in general, are active against some enveloped viruses, like COVID-19 coronavirus, due to the incorporation of the fatty acid into the lipid membrane of the viral envelope causing destabilisation of its bilayer. Broad beans (Vicia faba), grown in Northern Sudan, proved to incorporate high content of unsaturated fatty acids and in particular linoleic acid (46.41%). It forms a traditional meal in Sudan and in several Middle East countries. Hence, it is here recommended to be taken as the main meal in combination with sesame oil, as it is commonly practiced in Sudan. Theoretically, it has the potential to protect from COVID-19 coronavirus infections. This proposal needs to be confirmed by further experimental and clinical research.
Copyright © Sudanese Association of Pediatricians.

Entities:  

Keywords:  Broad beans; COVID-19 coronavirus; Fatty acids; Linoleic acid; Vicia faba

Year:  2020        PMID: 32528195      PMCID: PMC7282436          DOI: 10.24911/SJP.106-1585398078

Source DB:  PubMed          Journal:  Sudan J Paediatr        ISSN: 0256-4408


  5 in total

1.  Inactivation of enveloped viruses and killing of cells by fatty acids and monoglycerides.

Authors:  H Thormar; C E Isaacs; H R Brown; M R Barshatzky; T Pessolano
Journal:  Antimicrob Agents Chemother       Date:  1987-01       Impact factor: 5.191

2.  A substance in broad beans (Vicia faba) is protective against experimentally induced convulsions in mice.

Authors:  Mustafa Abdalla M Salih; Ali A Mustafa
Journal:  Epilepsy Behav       Date:  2007-11-05       Impact factor: 2.937

3.  Unsaturated free fatty acids inactivate animal enveloped viruses.

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Journal:  Arch Virol       Date:  1980       Impact factor: 2.574

4.  Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication.

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Journal:  Viruses       Date:  2019-01-16       Impact factor: 5.048

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  5 in total
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  4 in total

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