Literature DB >> 32525751

Survey of Principal Investigators in Biobanking: Knowledge, Attitudes, and Research Behaviors About Transgender and Gender-Diverse Patients.

Nat C Jones1,2, Monica E Reyes2, Gwendolyn P Quinn3, Matthew B Schabath1,2.   

Abstract

PURPOSE: Biobanks usually do not collect transgender and gender-diverse (TGD) demographic information, hindering research on cancer risk and biological effects related to gender-affirming interventions.
METHODS: In August 2019, 172 scientists involved in biobanking research at a single institution (H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL) were invited to complete a survey measuring knowledge and attitudes about TGD health and research practices. Quantitative and qualitative analyses were performed.
RESULTS: Among 47 respondents, there was high agreement (77%) regarding the importance of collecting TGD identities and histories of gender-affirming treatments with biospecimens, which was contrasted by low self-reported rates of respondents' biorepositories allowing for the entry of TGD identities (14.9%) and histories of gender-affirming interventions (8.5%). There was high interest in receiving education regarding the unique cancer health needs of TGD patients (74%), and knowledge questions yielded high percentages of "neutral" and "don't know or prefer not to answer" responses. After completing the survey, confidence in knowledge of health needs for TGD patients decreased significantly (48.9% were confident during the presurvey assessment v 36.2% in the postsurvey assessment; P < .001). Qualitative analysis of open-ended questions indicated overall support of TGD data inclusion in biobanks along with perceived barriers to inclusion of such data in biobanks.
CONCLUSION: To our knowledge, this was the first study of researchers to assess knowledge, attitudes, and research practices regarding TGD patients. Overall, there was limited knowledge about TGD health and cancer needs and low rates of TGD demographic data collection but a high interest in receiving education regarding this community.

Entities:  

Mesh:

Year:  2020        PMID: 32525751      PMCID: PMC7564131          DOI: 10.1200/OP.20.00193

Source DB:  PubMed          Journal:  JCO Oncol Pract        ISSN: 2688-1527


  16 in total

1.  Cancer risk in the transgender community.

Authors: 
Journal:  Lancet Oncol       Date:  2015-09       Impact factor: 41.316

Review 2.  Cancer and lesbian, gay, bisexual, transgender/transsexual, and queer/questioning (LGBTQ) populations.

Authors:  Gwendolyn P Quinn; Julian A Sanchez; Steven K Sutton; Susan T Vadaparampil; Giang T Nguyen; B Lee Green; Peter A Kanetsky; Matthew B Schabath
Journal:  CA Cancer J Clin       Date:  2015-07-17       Impact factor: 508.702

3.  Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer. Collaborative Group on Hormonal Factors in Breast Cancer.

Authors: 
Journal:  Lancet       Date:  1997-10-11       Impact factor: 79.321

Review 4.  Use of HRT and the subsequent risk of cancer.

Authors:  V Beral; E Banks; G Reeves; P Appleby
Journal:  J Epidemiol Biostat       Date:  1999

5.  A critical intervention in lesbian, gay, bisexual, and transgender health: knowledge and attitude outcomes among second-year medical students.

Authors:  Leah Kelley; Calvin L Chou; Suzanne L Dibble; Patricia A Robertson
Journal:  Teach Learn Med       Date:  2008 Jul-Sep       Impact factor: 2.414

6.  Attitudes and knowledge among obstetrician-gynecologists regarding lesbian patients and their health.

Authors:  Hasan M Abdessamad; Mark H Yudin; Lesley A Tarasoff; Kimberly D Radford; Lori E Ross
Journal:  J Womens Health (Larchmt)       Date:  2013-01       Impact factor: 2.681

Review 7.  Priorities for transgender medical and healthcare research.

Authors:  Jamie Feldman; George R Brown; Madeline B Deutsch; Wylie Hembree; Walter Meyer; Heino F L Meyer-Bahlburg; Vin Tangpricha; Guy TʼSjoen; Joshua D Safer
Journal:  Curr Opin Endocrinol Diabetes Obes       Date:  2016-04       Impact factor: 3.243

8.  Transgender-inclusive measures of sex/gender for population surveys: Mixed-methods evaluation and recommendations.

Authors:  Greta R Bauer; Jessica Braimoh; Ayden I Scheim; Christoffer Dharma
Journal:  PLoS One       Date:  2017-05-25       Impact factor: 3.240

Review 9.  Vocal Feminization for Transgender Women: Current Strategies and Patient Perspectives.

Authors:  Hyung-Tae Kim
Journal:  Int J Gen Med       Date:  2020-02-12

10.  Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence.

Authors: 
Journal:  Lancet       Date:  2019-08-29       Impact factor: 79.321

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