| Literature DB >> 32525493 |
Anja Mizdrak1, Kendra Telfer1, Artur Direito2, Linda J Cobiac3, Tony Blakely1,4, Christine L Cleghorn1, Nick Wilson1.
Abstract
BACKGROUND: Physical activity smartphone apps are a promising strategy to increase population physical activity, but it is unclear whether government mass media campaigns to promote these apps would be a cost-effective use of public funds.Entities:
Keywords: mHealth; mass media campaigns; mobile health; modeling; physical activity; smartphone apps
Mesh:
Year: 2020 PMID: 32525493 PMCID: PMC7317635 DOI: 10.2196/18014
Source DB: PubMed Journal: JMIR Mhealth Uhealth ISSN: 2291-5222 Impact factor: 4.773
Figure 1Flow chart of intervention conceptualization. Italicized text represents the percentage of the eligible population exposed to each step in the intervention pathway. NZ: New Zealand.
Intervention parameters and uncertainty distributions.
| Parameter | Value | Distribution | Source |
| Adult NZa population aware of mass media campaign, % (UIb) | 77.9 (70-83) | Beta | Based on awareness of previous health-related mass media campaign in NZ (Health Promotion Agency [ |
| Adult NZ population who downloaded a physical activity app, % (UI) | 31 (21-41) | Beta | Estimated based on the proportion of survey respondents who had downloaded a physical activity app to track behavior (Krebs and Duncan [ |
| Adult NZ population who used the physical activity app, % (UI) | 16 (10-36) | Beta | Based on the proportion of people likely to “take action” after a UK-based mass-media campaign to promote app use (Brannan et al, [ |
| Users who adhered to physical activity app (weighted annual average), % (UI) | 15 (10-21) | Beta | Weighted average of estimates of “app only” adherence from Guertler et al [ |
| Intervention increase in physical activity for those who adhered to the app (mins/week), n (SD) | 285 (43) | Normal | Reported increase of 1404 steps per day from recent meta-analysis of randomized controlled trials (Gal et al [ |
| Cost of a one-off national level mass media campaign (NZ $), n (SD %) | 2,883,000 (20) | Gamma | As per a similar NZ study for promoting a weight loss app, by Cleghorn et al [ |
aNZ: New Zealand.
bUI: uncertainty interval.
cMVPA: moderate-to-vigorous physical activity.
dMET: metabolic equivalent of task.
Figure 2Conceptual diagram of model. CHD: coronary heart disease; COPD: chronic obstructive pulmonary disease; LRTI: lower respiratory tract infection.
Health gains and cost-effectiveness of a mass media campaign to promote physical activity smartphone apps by age, sex, and ethnicity (lifetime gains, 3% discount rate).
| Sex, ethnicity | Age group (years) | QALYsa/1000 population (UIb) | Cost per QALY gained: ICERc, 2011 NZ $ (UI) | |
| All, all | All groups | 0.008 (0.002-0.021) | 81,000 (17,000-345,000) | |
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| Non-Māori | |||
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| <40 | 0.001 (0.000-0.003) | 606,000 (190,000-2,368,000) |
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| 40-60 | 0.008 (0.002-0.021) | 86,000 (16,000-384,000) |
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| 60-80 | 0.021 (0.006-0.055) | 27,000 (cost-savingd to 147,000) |
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| Māori | |||
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| <40 | 0.002 (0.001-0.006) | 354,000 (111,000-1,384,000) |
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| 40-60 | 0.018 (0.005-0.047) | 35,000 (2000-179,000) |
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| 60-80 | 0.031 (0.009-0.083) | 16,000 (cost-saving to 96,000) |
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| Non-Māori | |||
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| <40 | 0.002 (0.000-0.005) | 393,000 (120,000-1,499,000) |
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| 40-60 | 0.006 (0.002-0.017) | 119,000 (26,000-495,000) |
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| 60-80 | 0.023 (0.007-0.061) | 26,000 (cost-saving to 132,000) |
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| Māori | |||
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| <40 | 0.003 (0.001-0.009) | 196,000 (54,000-768,000) |
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| 40-60 | 0.019 (0.005-0.049) | 31,000 (0-158,000) |
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| 60-80 | 0.035 (0.010-0.094) | 15,000 (cost-saving to 87,000) |
aQALY: quality-adjusted life year.
bUI: uncertainty interval.
cICER: incremental cost-effectiveness ratio.
dNegative cost per QALY gained (ie, the intervention results in cost-savings to the health system).
Figure 3Probability of the modeled physical activity app promotion intervention being cost-effective for different cost-effectiveness thresholds (in cost per quality-adjusted life year gained).
Results for Māori (Indigenous population) with equity adjustment applied (lifetime gains, 3% discount rate).
| Sex, age (years) | QALYsa/1000 people (UIb) | Cost per QALY gained: ICERc, 2011 NZ $ (UI) | |
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| <40 | 0.002 (0.001-0.006) | 315,000 (92,000-1,191,000) |
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| 40-60 | 0.022 (0.006-0.058) | 30,000 (1000-142,000) |
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| 60-80 | 0.046 (0.012-0.126) | 11,000 (cost-savingd to 69,000) |
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| <40 | 0.004 (0.001-0.010) | 172,000 (43,000-669,000) |
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| 40-60 | 0.024 (0.006-0.062) | 26,000 (cost-saving to 130,000) |
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| 60-80 | 0.052 (0.014-0.137) | 10,000 (cost-saving to 64,000) |
aQALY: quality-adjusted life year.
bUI: uncertainty interval.
cICER: incremental cost-effectiveness ratio.
dNegative cost per QALY gained (ie, the intervention results in cost-savings to the health system).
Sensitivity and scenario analyses for a one-off national-level mass media campaign to promote smartphone apps for physical activity (expected value analysis, lifetime perspective, 3% discount rate, unless otherwise stated).
| Sensitivity/scenario analysesa | Health gain (QALYsb) | Net health system costs (NZ $) | Cost per QALY gained: ICERb (NZ $) |
| Base case analysis | 33 | 2,315,000 | 81,000 |
| Target age range set to 40-80 years of age (otherwise base case) | 30 | 2,387,000 | 80,000 |
| 5-year maintenance of additional physical activity levels followed by a return to preintervention levels (otherwise base case) | 126 | 241,146 | 2000 |
| 0% discount rate | 57 | 2,153,000 | 38,000 |
| 6% discount rate | 22 | 2,332,000 | 108,000 |
aExpected values given for all scenarios.
bQALY: quality-adjusted life year.
cICER: incremental cost-effectiveness ratio.
Figure 4Tornado plot showing the contribution of parameter uncertainty to overall uncertainty in the incremental cost-effectiveness ratio for the whole adult population.