Literature DB >> 32525143

Targeting and extending the eukaryotic druggable genome with natural products.

Hendrik Luesch1, John B MacMillan2.   

Abstract

Entities:  

Year:  2020        PMID： 32525143      PMCID： PMC7392165          DOI： 10.1039/d0np90021d

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


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  23 in total

Review 1.  Targeting and extending the eukaryotic druggable genome with natural products: cytoskeletal targets of natural products.

Authors:  April L Risinger; Lin Du
Journal:  Nat Prod Rep       Date:  2019-11-25       Impact factor: 13.423

2.  Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019.

Authors:  David J Newman; Gordon M Cragg
Journal:  J Nat Prod       Date:  2020-03-12       Impact factor: 4.050

Review 3.  Chemical diversity and mode of action of natural products targeting lipids in the eukaryotic cell membrane.

Authors:  Shinichi Nishimura; Nobuaki Matsumori
Journal:  Nat Prod Rep       Date:  2020-02-05       Impact factor: 13.423

Review 4.  Dietary natural products as epigenetic modifiers in aging-associated inflammation and disease.

Authors:  Levi W Evans; Matthew S Stratton; Bradley S Ferguson
Journal:  Nat Prod Rep       Date:  2020-01-29       Impact factor: 13.423

Review 5.  Synthetic lethality: a step forward for personalized medicine in cancer.

Authors:  Heena Jariyal; Frank Weinberg; Abhinav Achreja; Deepak Nagarath; Akshay Srivastava
Journal:  Drug Discov Today       Date:  2019-12-04       Impact factor: 7.851

Review 6.  Targeting eukaryotic proteases for natural products-based drug development.

Authors:  Fatma H Al-Awadhi; Hendrik Luesch
Journal:  Nat Prod Rep       Date:  2020-06-24       Impact factor: 13.423

Review 7.  Synthetic lethality as an engine for cancer drug target discovery.

Authors:  Alan Huang; Levi A Garraway; Alan Ashworth; Barbara Weber
Journal:  Nat Rev Drug Discov       Date:  2019-11-11       Impact factor: 84.694

8.  The druggable genome and support for target identification and validation in drug development.

Authors:  Chris Finan; Anna Gaulton; Felix A Kruger; R Thomas Lumbers; Tina Shah; Jorgen Engmann; Luana Galver; Ryan Kelley; Anneli Karlsson; Rita Santos; John P Overington; Aroon D Hingorani; Juan P Casas
Journal:  Sci Transl Med       Date:  2017-03-29       Impact factor: 17.956

Review 9.  A comprehensive map of molecular drug targets.

Authors:  Rita Santos; Oleg Ursu; Anna Gaulton; A Patrícia Bento; Ramesh S Donadi; Cristian G Bologa; Anneli Karlsson; Bissan Al-Lazikani; Anne Hersey; Tudor I Oprea; John P Overington
Journal:  Nat Rev Drug Discov       Date:  2016-12-02       Impact factor: 84.694

10.  The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction.

Authors:  J P Incardona; W Gaffield; R P Kapur; H Roelink
Journal:  Development       Date:  1998-09       Impact factor: 6.868
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  1 in total

1.  Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site.

Authors:  Susan Matthew; Qi-Yin Chen; Ranjala Ratnayake; Charles S Fermaintt; Daniel Lucena-Agell; Francesca Bonato; Andrea E Prota; Seok Ting Lim; Xiaomeng Wang; J Fernando Díaz; April L Risinger; Valerie J Paul; Maria Ángela Oliva; Hendrik Luesch
Journal:  Proc Natl Acad Sci U S A       Date:  2021-03-02       Impact factor: 11.205
  1 in total

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