| Literature DB >> 32524750 |
Madhukar S Patel1, Zubaida Mohamed1, Anand Ghanekar1, Gonzalo Sapisochin1, Ian McGilvray1, Blayne A Sayed1, Trevor Reichman1, Markus Selzner1, Jed A Gross1, Zita Galvin1, Mamatha Bhat1, Les Lilly1, Mark Cattral1, Nazia Selzner1.
Abstract
Paired organ exchange can be used to circumvent living donor-recipient ABO incompatibilities. Herein, we present the first case of successful liver paired exchange in North America. This 2-way swap required 4 simultaneous operations: 2 living donor hepatectomies and 2 living donor liver transplants. A nondirected anonymous living donor gift initiated this domino exchange, alleviating an ABO incompatibility in the other donor-recipient pair. With careful attention to ethical and logistical issues, paired liver exchange is a feasible option to expand the donor pool for incompatible living liver donor-recipient pairs.Entities:
Keywords: ABO incompatibility; clinical research/practice; donors and donation: living; donors and donation: paired exchange; liver transplantation/hepatology; liver transplantation: living donor
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Year: 2020 PMID： 32524750 DOI： 10.1111/ajt.16137
Source DB: PubMed Journal: Am J Transplant ISSN： 1600-6135 Impact factor: 8.086