Literature DB >> 32519617

Coronavirus Disease (COVID-19) in Kidney and Liver Transplant Patients: A Single-Center Experience.

Aydincan Akdur1, Emre Karakaya, Ebru H Ayvazoglu Soy, Omar Alshalabi, Mahir Kirnap, Hande Arslan, Gaye Ulubay, Koray Hekimoglu, Gokhan Moray, Mehmet Haberal.   

Abstract

OBJECTIVES: The novel 2019 coronavirus (COVID-19) was first described in December 2019 in Wuhan, China and subsequently announced as a pandemic on March 12, 2020. In several studies, solid-organ transplant recipients were reported to have higher risk for COVID-19. Here, we aimed to determine the frequency of COVID-19 in our kidney and liver transplant patients.
MATERIALS AND METHODS: Our study included 583 transplant patients who were admitted to our outpatient transplant clinics and emergency departments between March 1 and May 1, 2020. Seventy-four of them were liver transplant recipients (46 male, 28 female, of which 14 were pediatric and 60 were adult patients) and 509 of them were kidney transplant recipients (347 male, 162 female, of which 16 were pediatric and 493 were adult patients). We retrospectively evaluated demographic characteristics, currently used immunosuppressant treatment, present complaints, treatment and diagnosis of comorbid diseases, and results of COVID-19 tests.
RESULTS: Of 583 transplant recipients, 538 were seen in our outpatient transplant clinics and 45 were seen in our emergency departments. Of these, 18 patients who had had cough and fever were evaluated by respiratory clinic doctors, and nasopharyngeal swab samples were taken. One kidney transplant recipient had a positive COVID-19 test; he was followed with home isolation. He received treatment with hydroxychloroquine (400 mg/day). The other 17 patients had negative tests. There were no mortalities due to COVID-19.
CONCLUSIONS: Transplant patients also got affected during the COVID-19 pandemic. According to the data of our centers, this effect is not much more different from the normal population. We recommend that transplant recipients should be warned in terms of personal hygiene and should be closely monitored by organ transplant centers. If there is an indication for hospitalization, they should be followed in an isolated unit, with no aggressive changes made to immunosuppressive doses unless necessary.

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Year:  2020        PMID: 32519617     DOI: 10.6002/ect.2020.0193

Source DB:  PubMed          Journal:  Exp Clin Transplant        ISSN: 1304-0855            Impact factor:   0.938


  11 in total

1.  The Management of Immunosuppression in Kidney Transplant Recipients with COVID-19 Disease: An Update and Systematic Review of the Literature.

Authors:  Roberta Angelico; Francesca Blasi; Tommaso Maria Manzia; Luca Toti; Giuseppe Tisone; Roberto Cacciola
Journal:  Medicina (Kaunas)       Date:  2021-04-30       Impact factor: 2.430

Review 2.  A Systematic Review of COVID-19 Infection in Kidney Transplant Recipients: A Universal Effort to Preserve Patients' Lives and Allografts.

Authors:  Smaragdi Marinaki; Stathis Tsiakas; Maria Korogiannou; Konstantinos Grigorakos; Vassilios Papalois; Ioannis Boletis
Journal:  J Clin Med       Date:  2020-09-16       Impact factor: 4.241

3.  A Recipient and Donor Both Have COVID-19 Disease. Should We Perform a Liver Transplant?

Authors:  Adem Tuncer; Sami Akbulut; Adil Baskiran; Ezgi Erdal Karakas; Deniz Yavuz Baskiran; Brian Carr; Sezai Yilmaz
Journal:  J Gastrointest Cancer       Date:  2021-02-18

Review 4.  A Comprehensive Overview of the COVID-19 Literature: Machine Learning-Based Bibliometric Analysis.

Authors:  Alaa Abd-Alrazaq; Jens Schneider; Borbala Mifsud; Tanvir Alam; Mowafa Househ; Mounir Hamdi; Zubair Shah
Journal:  J Med Internet Res       Date:  2021-03-08       Impact factor: 5.428

5.  COVID-19 infection in pediatric solid organ transplant patients.

Authors:  Neha Bansal; Nadia Ovchinsky; Marc Foca; Jacqueline M Lamour; Debora Kogan-Liberman; Daphne T Hsu; Kimberly Beddows; Lincy Abraham; Maura Coburn; Ryan Cunningham; Trang Nguyen; Nicole Hayde
Journal:  Pediatr Transplant       Date:  2021-10-11

6.  Clinical characteristics and outcome of coronavirus disease 2019 infection in patients with solid organ transplants: A systematic review and meta-analysis.

Authors:  Wen An; Qiuyang Wang; Tae-Eun Kim; Ju-Seop Kang
Journal:  J Infect Public Health       Date:  2022-02-19       Impact factor: 3.718

Review 7.  Transplantation during the COVID-19 pandemic: nothing noble is accomplished without danger.

Authors:  Gabriele Spoletini; Giuseppe Bianco; Dario Graceffa; Quirino Lai
Journal:  BMC Gastroenterol       Date:  2020-08-06       Impact factor: 3.067

Review 8.  Kidney transplant recipients infected by COVID-19: Review of the initial published experience.

Authors:  Dimitrios Moris; Samuel J Kesseli; Andrew S Barbas
Journal:  Transpl Infect Dis       Date:  2020-08-07

9.  Short-term experiences of a liver transplant centre before and after the COVID-19 pandemic.

Authors:  Sibel Altunisik Toplu; Yasar Bayindir; Sezai Yilmaz; Murat Yalçınsoy; Baris Otlu; Adem Kose; Tevfik Tolga Sahin; Sami Akbulut; Burak Isik; Adil Başkiran; Cemalettin Koc
Journal:  Int J Clin Pract       Date:  2021-08-05       Impact factor: 3.149

10.  Outcomes of critically ill solid organ transplant patients with COVID-19 in the United States.

Authors:  Miklos Z Molnar; Anshul Bhalla; Ambreen Azhar; Makoto Tsujita; Manish Talwar; Vasanthi Balaraman; Amik Sodhi; Dipen Kadaria; James D Eason; Salim S Hayek; Steven G Coca; Shahzad Shaefi; Javier A Neyra; Shruti Gupta; David E Leaf; Csaba P Kovesdy
Journal:  Am J Transplant       Date:  2020-09-15       Impact factor: 9.369

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