Literature DB >> 32519117

[The role of ophthalmology in the COVID-19 pandemic].

Alexander C Rokohl1, Niklas Loreck2, Philomena A Wawer Matos2, Joel M Mor2, Sarah Zwingelberg2, Rafael S Grajewski2, Claus Cursiefen2, Ludwig M Heindl2.   

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19) has led to a worldwide pandemic. This pandemic presents a huge challenge for the healthcare system and also for ophthalmologists. Previous studies and case reports indicated that SARS-CoV‑2 also infects the conjunctiva resulting in conjunctivitis. In addition, infectious virus particles in the tear fluid can be potential sources of infection; however, the detection of SARS-CoV‑2 RNA in the tear fluid has rarely been successful. Although isolated conjunctival involvement is highly unlikely, at the current point in time of the COVID-19 pandemic, practically every patient examined by an ophthalmologist could be infected with SARS-CoV‑2. Therefore, protective and hygiene measures should currently be consistently followed to minimize the risk of spreading the virus. Currently, there are no treatment recommendations for conjunctivitis associated with COVID-19. Tear substitutes might be helpful for symptom relief but there is no evidence for a topical antiviral therapy. In the future ophthalmologists could play a decisive role in the screening of maculopathies that might occur during COVID-19 treatment using chloroquine or hydroxychloroquine.

Entities:  

Keywords:  Conjunctivitis; Corona-Virus-Disease-19; Coronavirus; Ophthalmology; SARS-CoV-2

Year:  2020        PMID: 32519117     DOI: 10.1007/s00347-020-01148-9

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  5 in total

1.  No secret hiding place on the ocular surface: what about after systemic SARS-CoV-2 infection?

Authors:  Alexander C Rokohl; Gerd Fätkenheuer; Claus Cursiefen; Ludwig M Heindl
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-05-18       Impact factor: 3.117

2.  Malignancy going viral: ACE2 and TMPRSS2 expression in conjunctival neoplastic diseases.

Authors:  Rafael S Grajewski; Alexander C Rokohl; Martina Becker; Friedrich Paulsen; Ludwig M Heindl
Journal:  Ann Anat       Date:  2020-12-17       Impact factor: 2.698

Review 3.  SARS-COV-2 and Ocular Surface: From Physiology to Pathology, a Route to Understand Transmission and Disease.

Authors:  Dalton de Freitas Santoro; Luciene Barbosa de Sousa; Niels O S Câmara; Denise de Freitas; Lauro Augusto de Oliveira
Journal:  Front Physiol       Date:  2021-02-12       Impact factor: 4.566

4.  No secret hiding place? Absence of SARS-CoV-2 on the ocular surface of 1145 hospitalized patients in a pandemic area.

Authors:  Alexander C Rokohl; Rafael S Grajewski; Philomena A Wawer Matos; Hannah-Leah Koch; Felix Dewald; Florian Klein; Gerd Fätkenheuer; Clara Lehmann; Claus Cursiefen; Ludwig M Heindl
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-01-29       Impact factor: 3.117

5.  More than loss of taste and smell: burning watering eyes in coronavirus disease 2019.

Authors:  Alexander C Rokohl; Niklas Loreck; Philomena A Wawer Matos; Sarah Zwingelberg; Max Augustin; Felix Dewald; Rafael S Grajewski; Florian Klein; Clara Lehmann; Ludwig M Heindl
Journal:  Clin Microbiol Infect       Date:  2020-08-21       Impact factor: 13.310

  5 in total

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