| Literature DB >> 325171 |
T M Dexter, M A Moore, A P Sheridan.
Abstract
A culture system is described in which bone marrow-derived adherent cells can support prolonged proliferation and differentiation of genetically incompatible stem cells and precursor cells. The results suggest that the reactive cells responsible in vivo for host transplantation resistance and for graft-versus-host disease are selectively lost or inhibited in such cultures, which may provide a vehicle for studying some of the cellular mechanisms involved in transplantation resistance.Entities:
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Year: 1977 PMID: 325171 PMCID: PMC2180693 DOI: 10.1084/jem.145.6.1612
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307