| Literature DB >> 32516953 |
Stefania Leuci1, Noemi Coppola1, Anna Turkina2, Maria Eleonora Bizzoca3, Gianfranco Favia4, Gianrico Spagnuolo1,2, Michele Davide Mignogna1.
Abstract
Early diagnosis of oral cancer through visual inspection followed by histopathological confirmation is a pivotal step for reducing rates of morbidity and mortality. There are several auxiliary devices used to improve oral examination. The purpose of this cross-sectional pilot study is to evaluate the sensitivity and specificity of the Visually Enhance Lesion Scope (VelScope) system when it is used by the general dentist after a yearly oral medicine training. Thirty-five patients with oral lesions were evaluated with clinical and VelScope examination by two general dentists, one of which trained with a specific course. A comparison of the histopathological results, clinical examination, and VelScope made by both dentists was performed through statistical analysis. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for detecting oral potentially malignant disorders (OPMDs) are 53.3%, 65%, 53.3%, 76.5% for unskilled dentist, 73.3%, 65%, 61.1%, 76.5% for skilled clinician. When both examiners use VelScope the values are 53.3%, 70%, 57.1%, 66.7% for unskilled general dentist (u-GD), 86.7%, 90%, 86.7%, 90% for skilled general dentist (s-GD). Improvement of a skilled general dentist for detecting malignancies is higher than inexperienced examiner when using VelScope. VelScope alone is unable to improve the general dentist's ability to detect malignancies, but it could be a useful adjunctive device for clinicians when a focused training program is performed.Entities:
Keywords: OSCC; VelScope; awareness; oral cancer; pre-cancer; screening
Year: 2020 PMID: 32516953 DOI: 10.3390/jcm9061754
Source DB: PubMed Journal: J Clin Med ISSN: 2077-0383 Impact factor: 4.241