| Literature DB >> 32516616 |
Donatella Valdembri1, Guido Serini2.
Abstract
In endothelial cells, trafficking of active α5β1 integrins and polarized fibronectin secretion are important for vascular morphogenesis. A new study unveils how the endothelial small GTPase RHOJ, by repressing trafficking of active α5β1 integrins, controls fibronectin polymerization and in vivo angiogenesis.Entities:
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Year: 2020 PMID： 32516616 DOI： 10.1016/j.cub.2020.04.004
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834