Literature DB >> 325166

Rat foetal endocrine pancreas in experimental diabetes.

L Aerts, F A van Assche.   

Abstract

The endocrine pancreas of foetuses and newborn rats of experimental diabetic mothers showed morphological and ultrastructural changes. Islet hypertrophy and beta cell hyperplasia were constantly present, but the beta cells of foetuses of severely diabetic mothers were degranulated. The ultrastructural changes indicated hyperfunction in the beta cells of foetuses of experimental diabetic mothers. The morphological changes mentioned were similar to those seen in human diabetic pregnancy.

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Year:  1977        PMID: 325166     DOI: 10.1677/joe.0.0730339

Source DB:  PubMed          Journal:  J Endocrinol        ISSN: 0022-0795            Impact factor:   4.286


  30 in total

1.  Evidence for an insulin resistance in the adult offspring of pregnant streptozotocin-diabetic rats.

Authors:  K Holemans; L Aerts; F A Van Assche
Journal:  Diabetologia       Date:  1991-02       Impact factor: 10.122

2.  Immunocytochemical study of the endocrine pancreas in the rat during normal pregnancy and during experimental diabetic pregnancy.

Authors:  F A Van Assche; W Gepts; L Aerts
Journal:  Diabetologia       Date:  1980-06       Impact factor: 10.122

3.  Chronic pulsatile hyperglycemia reduces insulin secretion and increases accumulation of reactive oxygen species in fetal sheep islets.

Authors:  Alice S Green; Xiaochuan Chen; Antoni R Macko; Miranda J Anderson; Amy C Kelly; Nathaniel J Hart; Ronald M Lynch; Sean W Limesand
Journal:  J Endocrinol       Date:  2011-12-19       Impact factor: 4.286

4.  Fetal hyperglycemia acutely induces persistent insulin resistance in skeletal muscle.

Authors:  Kok Lim Kua; Shanming Hu; Chunlin Wang; Jianrong Yao; Diana Dang; Alexander B Sawatzke; Jeffrey L Segar; Kai Wang; Andrew W Norris
Journal:  J Endocrinol       Date:  2019-07-01       Impact factor: 4.286

5.  Fetal macrosomia in diabetic multiparous animals.

Authors:  Y S Kim; Y Yoon; I Jatoi; Y Kim
Journal:  Diabetologia       Date:  1981-03       Impact factor: 10.122

6.  Hyperglycaemia induced by glucose infusion in the unrestrained pregnant rat during the last three days of gestation: metabolic and hormonal changes in the mother and the fetuses.

Authors:  A Ktorza; J R Girard; M F Kinebanyan; L Picon
Journal:  Diabetologia       Date:  1981-12       Impact factor: 10.122

7.  Gestational hyperglycaemia and insulin release by the fetal rat pancreas in vitro: effect of amino acids and glyceraldehyde.

Authors:  M T Bihoreau; A Ktorza; L Picon
Journal:  Diabetologia       Date:  1986-07       Impact factor: 10.122

8.  Skeletal growth of fetuses from streptozotocin diabetic rat mothers: in vivo and in vitro studies.

Authors:  E Heinze; U Vetter
Journal:  Diabetologia       Date:  1987-02       Impact factor: 10.122

9.  Endocrine profile and testicular histomorphometry in adult rat offspring of diabetic mothers.

Authors:  Gholamali Jelodar; Zabiholah Khaksar; Mohammad Pourahmadi
Journal:  J Physiol Sci       Date:  2009-06-18       Impact factor: 2.781

10.  The endocrine pancreas of the fetus from diabetic pregnant rat.

Authors:  A Kervran; M Guillaume; A Jost
Journal:  Diabetologia       Date:  1978-11       Impact factor: 10.122

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