| Literature DB >> 32516594 |
Jaeda C Coutinho-Budd1, Heather T Broihier2.
Abstract
In a recent issue of Nature, Lammert et al. demonstrate that DNA damage drives AIM2-mediated pyroptosis during normal brain development, preventing anxiety-like behaviors acquisition in adults and revealing an important role for non-apoptotic mechanisms of cell death during neurodevelopment.Entities:
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Year: 2020 PMID： 32516594 DOI： 10.1016/j.devcel.2020.05.013
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270