Literature DB >> 32516584

Cross-Presentation of Tumor Antigens Is Ruled by Synaptic Transfer of Vesicles among Dendritic Cell Subsets.

Sreekumar Balan1, Nina Bhardwaj2.   

Abstract

Migratory dendritic cells (DCs) in tumors transport antigens and share them with lymph node resident DCs through cross-presentation. In this issue of Cancer Cell, Ruhland et al. demonstrate that transport and transfer of tumor antigens in vesicles is a dominant pathway to load resident DCs for presentation to T cells.
Copyright © 2020. Published by Elsevier Inc.

Entities:  

Year:  2020        PMID： 32516584     DOI： 10.1016/j.ccell.2020.05.013

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  7 in total

Review 1.  Roles of exosomes in cancer chemotherapy resistance, progression, metastasis and immunity, and their clinical applications (Review).

Authors:  Xiaoyan Wang; Yuan Zhou; Kaiyang Ding
Journal:  Int J Oncol       Date:  2021-05-20       Impact factor: 5.650

Review 2.  Dendritic Cells: Behind the Scenes of T-Cell Infiltration into the Tumor Microenvironment.

Authors:  Valeria Lucarini; Ombretta Melaiu; Patrizia Tempora; Silvia D'Amico; Franco Locatelli; Doriana Fruci
Journal:  Cancers (Basel)       Date:  2021-01-23       Impact factor: 6.639

3.  Universal immunotherapeutic strategy for hepatocellular carcinoma with exosome vaccines that engage adaptive and innate immune responses.

Authors:  Bingfeng Zuo; Yang Zhang; Kangjie Zhao; Li Wu; Han Qi; Rong Yang; Xianjun Gao; Mengyuan Geng; Yingjie Wu; Renwei Jing; Qibing Zhou; Yiqi Seow; HaiFang Yin
Journal:  J Hematol Oncol       Date:  2022-04-29       Impact factor: 17.388

Review 4.  The roles of extracellular vesicles in the immune system.

Authors:  Edit I Buzas
Journal:  Nat Rev Immunol       Date:  2022-08-04       Impact factor: 108.555

Review 5.  Antigen transfer and its effect on vaccine-induced immune amplification and tolerance.

Authors:  Yingying Shi; Yichao Lu; Jian You
Journal:  Theranostics       Date:  2022-08-01       Impact factor: 11.600

6.  MMP2 and TLRs modulate immune responses in the tumor microenvironment.

Authors:  Luciana R Muniz-Bongers; Christopher B McClain; Mansi Saxena; Gerold Bongers; Miriam Merad; Nina Bhardwaj
Journal:  JCI Insight       Date:  2021-06-22

7.  Survival Advantage Following TAG-72 Antigen-Directed Cancer Surgery in Patients With Colorectal Carcinoma: Proposed Mechanisms of Action.

Authors:  Charles L Hitchcock; Stephen P Povoski; Cathy M Mojzisik; Edward W Martin
Journal:  Front Oncol       Date:  2021-12-07       Impact factor: 6.244
  7 in total

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