Literature DB >> 32516504

Characterization of drug-related problems and associated factors in ambulatory patients in China.

Xin Wang1, Jing Yang1, Xiaojia Yu1, Zihui Wang1, Huaguang Wang1, Lihong Liu1.   

Abstract

WHAT IS KNOWN AND
OBJECTIVE: This study aimed to investigate the prevalence and the type of drug-related problems (DRPs) in ambulatory patients and identify factors that may be associated with risk of DRPs.
METHODS: Consecutive patients were enrolled from pharmacist outpatient clinics between January 2018 and June 2019. The pharmacists performed a comprehensive assessment of the patient's drug therapy. The DRPs and recommendations were evaluated using the DOCUMENT classification system. RESULTS AND DISCUSSION: The study population consisted of 248 patients with a mean age of 72.55 ± 6.29. The patients had a mean of 7.55 ± 4.72 ongoing medications during patients' routine clinic visits. A total of 1188 DRPs were identified during the study period. An average of 4.79 DRPs per patient was detected. Sixty-two different traditional Chinese patent medicines (TCPMs) contributed to 102 DRPs. Drug selection (24.9%) was the most common DRP followed by under treated (24.2%) and monitoring needed (24.2%). The number of medications taken was the significant factor for DRPs. Pharmacists made 1092 recommendations to address the DRPs (an average 0.92 recommendations per DRP). A change in therapy was the most common recommendation (43.6%), followed by the category 'monitoring' (28.6%). The overall acceptance rate of clinical pharmacist recommendations was 88.7%. More than a half (51.6%) of all interventions were assigned a moderate level of clinical significance. WHAT IS NEW AND
CONCLUSION: Drug-related problems were commonly observed among ambulatory Chinese patients. Clinical pharmacists had a valuable role to play in identifying and solving the DRPs.
© 2020 John Wiley & Sons Ltd.

Entities:  

Keywords:  China; ambulatory patient; clinical pharmacist; drug-related problems; elderly

Year:  2020        PMID: 32516504     DOI: 10.1111/jcpt.13161

Source DB:  PubMed          Journal:  J Clin Pharm Ther        ISSN: 0269-4727            Impact factor:   2.512


  2 in total

1.  Prevalence and Associated Factors of Drug-Related Problems Among Older People: A Cross-Sectional Study at King Chulalongkorn Memorial Hospital in Bangkok.

Authors:  Annie Paisansirikul; Armeena Ketprayoon; Wannee Ittiwattanakul; Aisawan Petchlorlian
Journal:  Drugs Real World Outcomes       Date:  2020-11-12

2.  Identification and solution of drug-related problems in the neurology unit of a tertiary hospital in China.

Authors:  Pengpeng Liu; Guangyao Li; Mei Han; Chao Zhang
Journal:  BMC Pharmacol Toxicol       Date:  2021-10-26       Impact factor: 2.483

  2 in total

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