Janelle M James-McAlpine1,2, Lisa Vincze3, Jessica J Vanderlelie4, Anthony V Perkins1. 1. School of Medical Science, Menzies Health Institute Queensland, Griffith University, Southport, QLD 4015, Australia. 2. School of Nursing and Midwifery, Menzies Health Institute Queensland, Griffith University, Meadowbrook, QLD 4131, Australia. 3. School of Allied Health Sciences, Menzies Health Institute Queensland, Griffith University, Southport, QLD 4015, Australia. 4. Office of the Deputy Vice Chancellor, La Trobe University, Bundoora, VIC 3083, Australia.
Abstract
OBJECTIVE: To assess the quantity and focus of recent empirical research regarding the effect of micronutrient supplementation on live birth outcomes in low-risk pregnancies from high-income countries. DESIGN: A systematic quantitative literature review. SETTING: Low-risk pregnancies in World Bank-classified high-income countries, 2019. RESULTS: Using carefully selected search criteria, a total of 2475 publications were identified, of which seventeen papers met the inclusion criteria for this review. Data contributing to nine of the studies were sourced from four cohorts; research originated from ten countries. These cohorts exhibited a large number of participants, stable data and a low probability of bias. The most recent empirical data offered by these studies was 2011; the most historical was 1980. In total, fifty-five categorical outcome/supplement combinations were examined; 67·3 % reported no evidence of micronutrient supplementation influencing selected outcomes. CONCLUSIONS: A coordinated, cohesive and uniform empirical approach to future studies is required to determine what constitutes appropriate, effective and safe micronutrient supplementation in contemporary cohorts from high-income countries, and how this might influence pregnancy outcomes.
OBJECTIVE: To assess the quantity and focus of recent empirical research regarding the effect of micronutrient supplementation on live birth outcomes in low-risk pregnancies from high-income countries. DESIGN: A systematic quantitative literature review. SETTING: Low-risk pregnancies in World Bank-classified high-income countries, 2019. RESULTS: Using carefully selected search criteria, a total of 2475 publications were identified, of which seventeen papers met the inclusion criteria for this review. Data contributing to nine of the studies were sourced from four cohorts; research originated from ten countries. These cohorts exhibited a large number of participants, stable data and a low probability of bias. The most recent empirical data offered by these studies was 2011; the most historical was 1980. In total, fifty-five categorical outcome/supplement combinations were examined; 67·3 % reported no evidence of micronutrient supplementation influencing selected outcomes. CONCLUSIONS: A coordinated, cohesive and uniform empirical approach to future studies is required to determine what constitutes appropriate, effective and safe micronutrient supplementation in contemporary cohorts from high-income countries, and how this might influence pregnancy outcomes.
Entities:
Keywords:
Birth outcomes; High income; Micronutrients; Pregnancy; Supplements