Literature DB >> 32515404

Comprehensive overview of COVID-19 clinical trials.

Kiran Ejaz1, Tanveer Kauser2, Amnah Siddiqa3.   

Abstract

Here, we present an overview of the clinical trials that are currently being conducted or have concluded to date on COVID-19 globally. A comprehensive search was conducted to present 16 trial registries from around the world. Collectively, there are 1,528 trials reported for COVID-19 to date. Out of them, 50 studies included paediatric age group from day 0 to less than or equal to 18 years of age. A few 18 studies involve only females and 20 only males. There are 2 trials currently underway in Bangladesh, 4 in Pakistan and 13 in India. Overall, 940 trials are related to medicines and/or interventions. They include standard of care for any viral illness, antivirals, anti-inflammatory and immune altering medications. Two out of 10 vaccine trials are novel vaccines. It is knowledgeable and resourceful to reach out to the concerned sponsor if a physician thinks his patient can benefit from the trials in the region.

Entities:  

Keywords:  Coronavirus, 2019-nCoV, SARS-CoV-2, 2019nCoV, Clinical Trial, Asia.zzm321990

Mesh:

Year:  2020        PMID: 32515404     DOI: 10.5455/JPMA.37

Source DB:  PubMed          Journal:  J Pak Med Assoc        ISSN: 0030-9982            Impact factor:   0.781


  3 in total

1.  Perspectives on the use and risk of adverse events associated with cytokine-storm targeting antibodies and challenges associated with development of novel monoclonal antibodies for the treatment of COVID-19 clinical cases.

Authors:  Aishwarya Mary Johnson; Robert Barigye; Hariharan Saminathan
Journal:  Hum Vaccin Immunother       Date:  2021-05-11       Impact factor: 3.452

2.  regCOVID: Tracking publications of registered COVID-19 studies.

Authors:  Craig S Mayer; Vojtech Huser
Journal:  BMC Med Res Methodol       Date:  2022-08-10       Impact factor: 4.612

3.  The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days.

Authors:  Perrine Janiaud; Cathrine Axfors; Janneke Van't Hooft; Ramon Saccilotto; Arnav Agarwal; Christian Appenzeller-Herzog; Despina G Contopoulos-Ioannidis; Valentin Danchev; Ulrich Dirnagl; Hannah Ewald; Gerald Gartlehner; Steven N Goodman; Noah A Haber; Angeliki Diotima Ioannidis; John P A Ioannidis; Mark P Lythgoe; Wenyan Ma; Malcolm Macleod; Mario Malički; Joerg J Meerpohl; Yan Min; David Moher; Blin Nagavci; Florian Naudet; Christiane Pauli-Magnus; Jack W O'Sullivan; Nico Riedel; Jan A Roth; Mandy Sauermann; Stefan Schandelmaier; Andreas M Schmitt; Benjamin Speich; Paula R Williamson; Lars G Hemkens
Journal:  F1000Res       Date:  2020-10-02
  3 in total

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