Literature DB >> 32513765

Spastic paraparesis associated with advanced liver cirrhosis: a condition obscure in terms of treatment and prognosis.

Jaspreet Kaur1, Gautam Jesrani1, Monica Gupta2, Sarabmeet Singh Lehl1.   

Abstract

Hepatic myelopathy or spastic paraparesis of liver disease is an insidious onset condition with pure motor spastic paraparesis without sensory, bladder or bowel involvement in patients with chronic liver disease, in which the neurological dysfunction cannot be explained by other causes. It is a rare, relentlessly progressive and mostly irreversible neurological complication resulting from portosystemic shunts occurring spontaneously, created surgically or due to 'functional shunting'. In some cases, no evidence of shunting is elicitable due to difficulty in locating the hidden collaterals. We report this rare case of a 33-year-old man with chronic liver disease presenting with spastic paraparesis after 11 months of resolution of an episode of hepatic encephalopathy. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  alcoholic liver disease; cirrhosis; spinal cord

Mesh:

Substances:

Year:  2020        PMID: 32513765      PMCID: PMC7282303          DOI: 10.1136/bcr-2020-235090

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  21 in total

1.  Portal-systemic myelopathy after transjugular intrahepatic portosystemic shunt creation: report of four cases.

Authors:  M Q Wang; M D Dake; Z P Cui; Z Q Wang; Y A Gao
Journal:  J Vasc Interv Radiol       Date:  2001-07       Impact factor: 3.464

2.  Hepato-lenticular degeneration; a case associated with postero-lateral column degeneration.

Authors:  A D LEIGH; W I CARD
Journal:  J Neuropathol Exp Neurol       Date:  1949-07       Impact factor: 3.685

3.  Postshunt myelopathy.

Authors:  V G Bain; R J Bailey; J H Jhamandas
Journal:  J Clin Gastroenterol       Date:  1991-10       Impact factor: 3.062

4.  Hepatic myelopathy with spastic paraparesis.

Authors:  Ufuk Utku; Talip Asil; Kemal Balci; Ilkay Uzunca; Yahya Celik
Journal:  Clin Neurol Neurosurg       Date:  2004-11-10       Impact factor: 1.876

5.  Portal-systemic myelopathy after portacaval shunt surgery.

Authors:  E Lebovics; R E DeMatteo; F Schaffner; S Gendelman
Journal:  Arch Intern Med       Date:  1985-10

6.  Hepatic myelopathy: an unusual neurological complication of chronic liver disease presenting as quadriparesis.

Authors:  Prakash Kori; Ritesh Sahu; Anupam Jaiswal; Rakesh Shukla
Journal:  BMJ Case Rep       Date:  2013-06-07

7.  Hepatic myelopathy: an unusual neurological complication of advanced hepatic disease.

Authors:  E Sobukawa; K Sakimura; S Hoshino; M Hoshino; K Miyoshi
Journal:  Intern Med       Date:  1994-11       Impact factor: 1.271

8.  Prevalence and Clinical Characteristics of Spontaneous Splenorenal Shunt in Liver Cirrhosis: A Retrospective Observational Study Based on Contrast-Enhanced Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) Scans.

Authors:  Xingshun Qi; Xiaolong Qi; Yongguo Zhang; Xiaodong Shao; Chunyan Wu; Yongji Wang; Ran Wang; Xintong Zhang; Han Deng; Feifei Hou; Jing Li; Xiaozhong Guo
Journal:  Med Sci Monit       Date:  2017-05-25

9.  Alcoholic Myelopathy and Nutritional Deficiency.

Authors:  Haruki Koike; Tomohiko Nakamura; Shohei Ikeda; Mie Takahashi; Yuichi Kawagashira; Masahiro Iijima; Masahisa Katsuno; Gen Sobue
Journal:  Intern Med       Date:  2017-01-01       Impact factor: 1.271

10.  The effect of fecal microbiota transplantation on Hepatic myelopathy: A case report.

Authors:  Lin Sun; Jun Li; Li-Li Lan; Xiao-An Li
Journal:  Medicine (Baltimore)       Date:  2019-07       Impact factor: 1.817

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