Sarah R Hatt1, David A Leske1, Yolanda S Castañeda2, Suzanne M Wernimont1, Laura Liebermann1, Christina S Cheng-Patel2, Eileen E Birch3, Jonathan M Holmes4. 1. Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota. 2. Retina Foundation of the Southwest, Dallas, Texas. 3. Retina Foundation of the Southwest, Dallas, Texas; Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas. 4. Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota. Electronic address: holmes.jonathan@mayo.edu.
Abstract
PURPOSE: To evaluate the effect of residual amblyopia on functional vision and eye-related quality of life (ER-QOL) in children and their families using the Pediatric Eye Questionnaire (PedEyeQ). DESIGN: Prospective cross-sectional study METHODS: Seventeen children with residual amblyopia (no current treatment except glasses), 48 visually normal controls without glasses and 19 controls wearing glasses (aged 8-11 years) completed the Child 5-11 year PedEyeQ. One parent for each child completed the Proxy 5-11 PedEyeQ, Parent PedEyeQ. Rasch-calibrated domain scores were calculated for each questionnaire domain and compared between amblyopic children and controls. RESULTS: PedEyeQ scores were significantly lower (worse) for children with residual amblyopia than for controls without glasses across all domains; Child PedEyeQ greatest mean difference 18 points worse on functional vision domain (95% CI -29 to -7; P<.001); Proxy PedEyeQ greatest mean difference 31 points worse on functional vision domain (95% CI -39 to -24; P<.001); Parent PedEyeQ greatest mean difference 34 points worse on the worry about the child's eye condition domain (95% CI -46 to -22; P<.001). Compared with controls wearing glasses, PedEyeQ scores were lower for residual amblyopia on the Child frustration / worry domain (P=.03), on four of five Proxy domains (P≤ .05) and on three of four Parent domains (P≤ .05). CONCLUSIONS: Residual amblyopia affects functional vision and ER-QOL in children. Parents of amblyopic children also experience lower quality of life. These data help broaden our understanding of the everyday-life impact of childhood residual amblyopia.
PURPOSE: To evaluate the effect of residual amblyopia on functional vision and eye-related quality of life (ER-QOL) in children and their families using the Pediatric Eye Questionnaire (PedEyeQ). DESIGN: Prospective cross-sectional study METHODS: Seventeen children with residual amblyopia (no current treatment except glasses), 48 visually normal controls without glasses and 19 controls wearing glasses (aged 8-11 years) completed the Child 5-11 year PedEyeQ. One parent for each child completed the Proxy 5-11 PedEyeQ, Parent PedEyeQ. Rasch-calibrated domain scores were calculated for each questionnaire domain and compared between amblyopic children and controls. RESULTS: PedEyeQ scores were significantly lower (worse) for children with residual amblyopia than for controls without glasses across all domains; Child PedEyeQ greatest mean difference 18 points worse on functional vision domain (95% CI -29 to -7; P<.001); Proxy PedEyeQ greatest mean difference 31 points worse on functional vision domain (95% CI -39 to -24; P<.001); Parent PedEyeQ greatest mean difference 34 points worse on the worry about the child's eye condition domain (95% CI -46 to -22; P<.001). Compared with controls wearing glasses, PedEyeQ scores were lower for residual amblyopia on the Child frustration / worry domain (P=.03), on four of five Proxy domains (P≤ .05) and on three of four Parent domains (P≤ .05). CONCLUSIONS: Residual amblyopia affects functional vision and ER-QOL in children. Parents of amblyopic children also experience lower quality of life. These data help broaden our understanding of the everyday-life impact of childhood residual amblyopia.
Authors: David A Leske; Sarah R Hatt; Suzanne M Wernimont; Yolanda S Castañeda; Christina S Cheng-Patel; Laura Liebermann; Eileen E Birch; Jonathan M Holmes Journal: J AAPOS Date: 2021-02-16 Impact factor: 1.220
Authors: Sarah R Hatt; David A Leske; Suzanne M Wernimont; Erick D Bothun; Eileen E Birch; Jonathan M Holmes Journal: J Binocul Vis Ocul Motil Date: 2022-02-01
Authors: Eileen E Birch; Yolanda S Castañeda; Christina S Cheng-Patel; Sarah E Morale; Krista R Kelly; Reed M Jost; Lindsey A Hudgins; David A Leske; Jonathan M Holmes Journal: Invest Ophthalmol Vis Sci Date: 2020-09-01 Impact factor: 4.799