| Literature DB >> 32509345 |
Grzegorz Gielerak1, Paweł Krzesiński1, Katarzyna Piotrowicz1, Piotr Murawski1, Andrzej Skrobowski1, Adam Stańczyk1, Agata Galas1, Beata Uziębło-Życzkowska1, Anna Kaźmierczak-Dziuk1, Joanna Maksimczuk1, Sylwia Miernik-Podleśko1, Monika Grzęda1, Emilia Sopolińska1, Marek Kiliszek1, Lidia Wojda1.
Abstract
The MIL-SCORE (Equalization of Accessibility to Cardiology Prophylaxis and Care for Professional Soldiers) program was designed to assess the prevalence and management of cardiovascular risk factors in a population of Polish soldiers. We aimed to describe the prevalence of cardiovascular risk factors in the MIL-SCORE population with respect to age. This observational cross-sectional study enrolled 6440 soldiers (97% male) who underwent a medical history, physical examination, and laboratory tests to assess cardiovascular risk. Almost half of the recruited soldiers were past or current smokers (46%). A sedentary lifestyle was reported in almost one-third of those over 40 years of age. The prevalence of hypertension in a subgroup over 50 years of age was almost 45%. However, the percentage of unsatisfactory blood pressure control was higher among soldiers below 40 years of age. The prevalence of overweight and obese soldiers increased with age and reached 58% and 27%, respectively, in those over 50 years of age. Total cholesterol was increased in over one-half of subjects, and the prevalence of abnormal low-density lipoprotein cholesterol was even higher (60%). Triglycerides were increased in 36% of soldiers, and low high-density lipoprotein cholesterol and hyperglycemia were reported in 13% and 16% of soldiers, respectively. In the >50 years of age subgroup, high and very high cardiovascular risk scores were observed in almost one-third of soldiers. The relative risk assessed in younger subgroups was moderate or high. The results from the MIL-SCORE program suggest that Polish soldiers have multiple cardiovascular risk factors and mirror trends seen in the general population. Preventive programs aimed at early cardiovascular risk assessment and modification are strongly needed in this population.Entities:
Year: 2020 PMID: 32509345 PMCID: PMC7251455 DOI: 10.1155/2020/3973526
Source DB: PubMed Journal: Cardiol Res Pract ISSN: 2090-0597 Impact factor: 1.866
Sociodemographic data.
| Total | 20–30 years of age | 31–40 years of age | 41–50 years of age | >50 years of age |
| |
|---|---|---|---|---|---|---|
| Gender (male/female)6440 | 6245/195 (97.0/3.0) | 2237/87 (96.3/3.7) | 2384/87 (96.5/3.5) | 1325/18 (98.7/1/3) | 299/3 (99.0/1.0) | 0.00003 |
| Age (years)6440 | 34.9 ± 8.1 | 26.8 ± 2.4 | 35.2 ± 2.9 | 44.3 ± 2.8 | 54.0 ± 3.1 | |
| Residence (countryside/town)6169 | 1788/4381 (30.0/70.0) | 798/1460 (35.3/64.6) | 703/1692 (29.4/70.6) | 252/1008 (20.0/80.0) | 35/221 (13.7/86.3) | <0.00001 |
|
| ||||||
| Coronary artery disease | 732 (11.6) | 126 (5.4) | 268 (10.9) | 273 (21.1) | 65 (24.4) | <0.00001 |
| Hypertension | 1302 (20.6) | 332 (14.3) | 541 (22.1) | 348 (26.8) | 81 (30.5) | <0.00001 |
| Stroke | 275 (4.3) | 46 (2.0) | 112 (4.6) | 90 (6.9) | 27 (10.2) | <0.00001 |
| Diabetes | 695 (11.0) | 157 (6.8) | 281 (11.5) | 224 (17.3) | 33 (12.4) | <0.00001 |
|
| ||||||
| Yes/current | 2933 (46.2)/1844 (62.9) | 1069 (46.8)/772 (72.2) | 1149 (47.3)/743 (64.7) | 551 (43.1)/282 (51.1) | 113 (44.5)/47 (41.6) | 0.075/<0.00001 |
| Smoking: pack-years (median, interquartile range) | 6 (2.5–11.25) | 4 (1.6–7.0) | 7 (3.0–12.0) | 11 (5.0–20.0) | 18.9 (10.0–30.0) | <0.0001 |
|
| ||||||
| Occasional | 1051 (16.7) | 213 (9.2) | 361 (14.8) | 400 (30.9) | 77 (29.5) | <0.00001 |
| Moderate | 2773 (43.9) | 1307 (56.5) | 1068 (43.7) | 335 (25.9) | 63 (24.1) | |
| High | 2487 (39.4) | 793 (34.3) | 1015 (41.5) | 558 (43.2) | 121 (46.4) | |
Data presented as mean ± standard deviation (SD) and number (percentage), respectively; Among smokers responding yes.
Basic clinical characteristics.
| Total | 20–30 years of age | 31–40 years of age | 41–50 years of age | >50 years of age |
| |
|---|---|---|---|---|---|---|
| HR (bpm)6311 | 73.7 ± 11.8 | 74.0 ± 11.7 | 73.9 ± 12.0 | 73.2 ± 11.3 | 72.2 ± 12.2 | 0.033 |
| SBP (mmHg)6304 | 134.7 ± 16.5 | 132.7 ± 15.8 | 134.8 ± 16.2 | 137.7 ± 17.6 | 137.4 ± 18.5 | <0.00001 |
| DBP (mmHg)6304 | 83.1 ± 11.4 | 79.5 ± 10.6 | 83.6 ± 10.8 | 87.4 ± 10.8 | 88.0 ± 12.4 | <0.00001 |
| BP = 130–139/85–89 (mmHg)6304 | 1006 (16.0) | 358 (15.5) | 378 (15.5) | 225 (17.4) | 45 (17.1) | <0.00001 |
| BP = 140–159/90–99 (mmHg)6304 | 2403 (38.1) | 754 (32.6) | 1003 (41.1) | 535 (41.4) | 111 (42.2) | <0.00001 |
| BP = 160–179/100–109 (mmHg)6304 | 708 (11.2) | 163 (7.0) | 268 (11.0) | 222 (17.2) | 55 (20.9) | <0.00001 |
| BP > 180/110 (mmHg)6304 | 158 (2.5) | 27 (1.2) | 55 (2.2) | 63 (4.9) | 13 (4.9) | <0.00001 |
| BMI (kg/m2)6316 | 26.7 ± 3.3 | 25.6 ± 2.9 | 26.8 ± 3.1 | 28.0 ± 3.5 | 28.2 ± 3.3 | <0.00001 |
| Overweight (BMI 25–29.9 kg/m2)6316 | 3447 (54.6) | 1152 (49.8) | 1407 (57.5) | 735 (56.9) | 153 (58.2) | <0.00001 |
| Obesity (BMI ≥30.0 kg/m2)6316 | 893 (14.1) | 157 (6.8) | 345 (14.1) | 320 (24.8) | 71 (27.0) | <0.00001 |
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| ||||||
| Coronary artery disease | 14 (0.2) | 0 (0.0) | 0 (0.0) | 5 (0.4) | 9 (3.4) | <0.00001 |
| Myocardial infarction | 10 (0.2) | 0 (0.0) | 0 (0.0) | 7 (0.5) | 3 (1.1) | <0.00001 |
| Chronic kidney disease | 11 (0.2) | 1 (0.04) | 5 (0.2) | 5 (0.4) | 0 (0.0) | 0.101 |
| Diabetes mellitus | 63 (1.0) | 0 (0.0) | 6 (0.24) | 39 (3.0) | 18 (6.8) | <0.00001 |
| Chronic obstructive pulmonary disease | 10 (0.2) | 0 (0.0) | 4 (0.2) | 4 (0.3) | 2 (0.8) | 0.009 |
| Hypertension | 834 (13.7) | 122 (5.3) | 260 (10.6) | 333 (25.7) | 1119 (44.7) | <0.00001 |
| Hypertension in medical history and office BP ≥140/90 mmHg | 717 (86.0) | 90 (73.8) | 237 (91.1) | 292 (88.0) | 98 (82.4) | — |
| Declared well home BP control: confirmed well BP control758 | 293 (38.7)/465 (61.3) | 24 (23.8)/77 (76.2) | 67 (28.3)/170 (71.7) | 145 (47.2)/162 (52.8) | 57 (50.4)/56 (49.6) | <0.00001 |
Data presented as mean ± standard deviation (SD) and number (percentage) p value not calculated (very low prevalence). BP: blood pressure; DBP: diastolic blood pressure; BMI: body mass index; HR: heart rate; SBP: systolic blood pressure.
The results of laboratory tests.
| Total | 20–30 years of age | 31–40 years of age | 41–50 years of age | >50 years of age |
| |
|---|---|---|---|---|---|---|
| Glucose (mg/dl)6255 | 88.8 ± 23.2 | 83.8 ± 20.7 | 88.3 ± 17.3 | 95.2 ± 23.8 | 106.1 ± 53.7 | <0.00001 |
| TC (mg/dl)6440 | 197.5 ± 42.0 | 181.5 ± 37.0 | 202.0 ± 39.2 | 215.1 ± 44.2 | 211.4 ± 48.4 | <0.00001 |
| TG (mg/dl)6285 | 152.0 ± 121.3 | 128.3 ± 88.2 | 158.7 ± 117.9 | 180.9 ± 167.7 | 156.5 ± 91.6 | <0.00001 |
| LDL-C (mg/dl)6440 | 128.3 ± 36.8 | 114.6 ± 32.2 | 131.8 ± 35.1 | 144.3 ± 38.5 | 141.6 ± 38.5 | <0.00001 |
| HDL-C (mg/dl)6262 | 52.7 ± 12.7 | 53.4 ± 12.5 | 52.7 ± 13.0 | 51.6 ± 12.6 | 52.0 ± 11.5 | 0.0007 |
| Glucose >100 mg/dl6255 | 993 (15.9) | 189 (8.3) | 366 (15.0) | 322 (25.2) | 116 (45.3) | <0.00001 |
| T-C >190 mg/dl6440 | 3357 (52.1) | 820 (35.3) | 1430 (57.9) | 937 (69.8) | 170 (56.3) | <0.00001 |
| LDL-C >115 mg/dl6245 | 3844 (59.8) | 1064 (46.1) | 1604 (66.3) | 989 (78.2) | 187 (74.2) | <0.00001 |
| TG >150 mg/dl6285 | 2274 (36.2) | 606 (26.3) | 955 (39.1) | 608 (47.4) | 105 (40.7) | <0.00001 |
| HDL-C <40 mg/dl (men) and <46 mg/dl (women)6262 | 823 (13.1) | 262 (11.4) | 328 (13.5) | 200 (15.7) | 33 (12.9) | 0.003 |
Data presented as mean ± standard deviation (SD) and number (percentage). HDL: high density lipoproteins cholesterol; LDL-C: low density lipoproteins cholesterol; TC: total cholesterol; TG: triglycerides.
Cardiovascular risk assessment and selected single risk factors by age.
| Total | 20–30 years of age | 31–40 years of age | 41–50 years of age | >50 years of age |
| |
|---|---|---|---|---|---|---|
|
| ||||||
| Mean SCORE | 2.4 ± 1.5 | 2.4 ± 1.3 | 2.7 ± 1.5 | 1.5 ± 1.0 | 4.3 ± 2.5 | <0.00001 |
| SCORE < 1% | 9 (0.2) | 0 (0.0) | 0 (0.0) | 9 (0.8) | 0 (0.0) | <0.00001 |
| SCORE ≥1 and <5% | 5479 (91.5) | 2080 (93.0) | 2091 (89.5) | 1161 (97.5) | 147 (66.5) | |
| SCORE ≥5% and <10% | 472 (7.9) | 155 (6.9) | 237 (10.2) | 18 (1.5) | 62 (28.1) | |
| SCORE ≥10% | 25 (0.4) | 2 (0.1) | 8 (0.3) | 3 (0.3) | 12 (5.4) | |
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| BP >180/110 mmHg6304 | 158 (2.5) | 27 (1.2) | 55 (2.2) | 63 (4.9) | 13 (4.9) | <0.00001 |
| T-C >310 mg/dl6440 | 89 (1.4) | 8 (0.3) | 37 (1.5) | 35 (2.6) | 9 (3.0) | <0.00001 |
| Coronary artery disease6333 | 14 (0.2) | 0 (0.0) | 0 (0.0) | 5 (0.4) | 9 (3.4) | <0.00001 |
| Chronic kidney disease6333 | 11 (0.2) | 1 (0.04) | 5 (0.2) | 5 (0.4) | 0 (0.0) | 0.101 |
| Diabetes mellitus6333 | 63 (1.0) | 0 (0.0) | 6 (0.24) | 39 (3.0) | 18 (6.8) | <0.00001 |
Data presented as number (percentage). Relative risk. BP: blood pressure; SCORE: systematic coronary risk evaluation.
Figure 1Distribution of risk factors divided by age (age groups: 20–30, 31–40, 41–50 and >50 years of age). Scale on the left shows percentage of soldiers with risk factor. Obesity: BMI >30 kg/m2; hypercholesterolemia: LDL cholesterol >115 mg/dl.