Ramya Ananthakrishnan1, Nalini Krishnan1, J Gurukartick1,2, Lakshmi Murali3, Hemant Deepak Shewade4,5, Anil G Jacob5, M M Samy3, D Dheenadayal3, O P Aslesh6, Ganesh Marimuthu1. 1. Resource Group for Education and Advocacy for Community Health (REACH), Chennai, India. 2. Government Mohan Kumaramangalam Medical College, Salem, India. 3. State TB cell, Department of Health and Family Welfare,, Chennai, India. 4. International Union Against Tuberculosis and Lung Disease (The Union), Paris, France. 5. The Union South-East Asia Office, New Delhi, India. 6. Government Medical College, Thrissur, India.
Abstract
Background: India's national tuberculosis (TB) programme recommends that among patients with diabetes mellitus and TB, fasting blood glucose (FBG) be recorded at baseline, the end of intensive phase and the end of continuation phase of TB treatment. We conducted this operational research in select districts of Tamil Nadu, India, in 2016 to determine the availability of blood glucose records and glycemic control status during TB treatment. Methods: This was a descriptive study involving secondary programme data. Glycemic control during TB treatment was 'optimal' if both baseline and end of intensive phase FBG (during TB treatment) were <130 mg/dl. In the absence of FBG, we used random blood glucose (RBG), with <180 mg/dl as the cut off. Results: Of 438 patients, FBG at baseline, the end of intensive phase and the end of continuation phase were each available in <20%. Glycemic control status was known for 94% (412/438) patients at baseline and for 91% (400/438) during TB treatment. Among those with known glycemic status, glycemic control was not optimal in 77% of patients (316/412) at baseline and in 84% (337/400) during TB treatment. The proportion of patients with unfavourable TB treatment outcomes at the end of intensive phase was 11% (46/438) and at the end of continuation phase was 5% (21/438). We decided against assessing factors associated with glycemic control during TB treatment and association between glycemic control and TB treatment outcomes because glycemic control assessment, if any, was based mostly on RBG values. Conclusion: Among patients with diabetes and tuberculosis, recording of FBG during tuberculosis treatment requires urgent attention. Copyright:
Background: India's national tuberculosis (TB) programme recommends that among patients with diabetes mellitus and TB, fasting blood glucose (FBG) be recorded at baseline, the end of intensive phase and the end of continuation phase of TB treatment. We conducted this operational research in select districts of Tamil Nadu, India, in 2016 to determine the availability of blood glucose records and glycemic control status during TB treatment. Methods: This was a descriptive study involving secondary programme data. Glycemic control during TB treatment was 'optimal' if both baseline and end of intensive phase FBG (during TB treatment) were <130 mg/dl. In the absence of FBG, we used random blood glucose (RBG), with <180 mg/dl as the cut off. Results: Of 438 patients, FBG at baseline, the end of intensive phase and the end of continuation phase were each available in <20%. Glycemic control status was known for 94% (412/438) patients at baseline and for 91% (400/438) during TB treatment. Among those with known glycemic status, glycemic control was not optimal in 77% of patients (316/412) at baseline and in 84% (337/400) during TB treatment. The proportion of patients with unfavourable TB treatment outcomes at the end of intensive phase was 11% (46/438) and at the end of continuation phase was 5% (21/438). We decided against assessing factors associated with glycemic control during TB treatment and association between glycemic control and TB treatment outcomes because glycemic control assessment, if any, was based mostly on RBG values. Conclusion: Among patients with diabetes and tuberculosis, recording of FBG during tuberculosis treatment requires urgent attention. Copyright:
Authors: A D Harries; A M V Kumar; S Satyanarayana; Y Lin; K C Takarinda; H Tweya; A J Reid; R Zachariah Journal: Public Health Action Date: 2015-09-21
Authors: Anthony D Harries; Ajay M V Kumar; Adam Karpati; Andreas Jahn; Gerald P Douglas; Oliver J Gadabu; Frank Chimbwandira; Rony Zachariah Journal: Trop Med Int Health Date: 2015-03-31 Impact factor: 2.622
Authors: Daniel Faurholt-Jepsen; Nyagosya Range; George PrayGod; Kidola Jeremiah; Maria Faurholt-Jepsen; Martine G Aabye; John Changalucha; Dirk L Christensen; Harleen M S Grewal; Torben Martinussen; Henrik Krarup; Daniel R Witte; Aase B Andersen; Henrik Friis Journal: Trop Med Int Health Date: 2013-05-06 Impact factor: 2.622