Betina Soldateli1,2, Margaret Parker3, Patrice Melvin4, Munish Gupta5, Mandy Belfort6. 1. Department of Pediatric Newborn Medicine, Brigham & Women's Hospital, Boston, MA, USA. betinasoldateli@hotmail.com. 2. Department of Nutrition, Federal University of Rio Grande do Sul, Porto Alegre, Brazil. betinasoldateli@hotmail.com. 3. Department of Pediatrics, Boston Medical Center, Boston, MA, USA. 4. Program for Patient Safety and Quality, Boston Children's Hospital, Boston, MA, USA. 5. Dept. of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA. 6. Department of Pediatric Newborn Medicine, Brigham & Women's Hospital, Boston, MA, USA.
Abstract
OBJECTIVES: Quantify associations of human milk feeding with in-hospital growth and examine differences by human milk type (maternal or donor). STUDY DESIGN: We included infants born <33 weeks' gestation and <1500 g from 9 Neonatal Intensive Care Units (n = 1429). We estimated associations of percent of visit days fed any human milk (maternal or donor) and percent of days fed donor milk with weight, length, and head z-scores at discharge or transfer using a linear mixed model, adjusting for birth size and other covariates. RESULTS: Any human milk feeding was not associated with growth outcomes. Infants fed donor milk on ≥50% of days had less favorable growth vs. those fed <50% [z-scores-weight: -1.1 vs. -0.7 (p = 0.04); length: -1.5 vs. -1.1 (p = 0.04); head -1.0 vs. -0.3 (p < 0.01)]. CONCLUSIONS: Fortified human milk was not associated with impaired growth compared with preterm formula.
OBJECTIVES: Quantify associations of human milk feeding with in-hospital growth and examine differences by human milk type (maternal or donor). STUDY DESIGN: We included infants born <33 weeks' gestation and <1500 g from 9 Neonatal Intensive Care Units (n = 1429). We estimated associations of percent of visit days fed any human milk (maternal or donor) and percent of days fed donor milk with weight, length, and head z-scores at discharge or transfer using a linear mixed model, adjusting for birth size and other covariates. RESULTS: Any human milk feeding was not associated with growth outcomes. Infants fed donor milk on ≥50% of days had less favorable growth vs. those fed <50% [z-scores-weight: -1.1 vs. -0.7 (p = 0.04); length: -1.5 vs. -1.1 (p = 0.04); head -1.0 vs. -0.3 (p < 0.01)]. CONCLUSIONS: Fortified human milk was not associated with impaired growth compared with preterm formula.
Authors: Paula M Sisk; Tinisha M Lambeth; Mario A Rojas; Teisha Lightbourne; Maria Barahona; Evelyn Anthony; Sam T Auringer Journal: Am J Perinatol Date: 2016-12-09 Impact factor: 1.862