OBJECTIVE: To investigate cyclophilin A in early second trimester of pregnancy before the onset of preeclampsia. METHODS: In this prospective case-control study, 51 pregnant women whose serum were collected and stored and who developed preeclampsia in later follow-up and 41 pregnant women as control group were included. RESULTS: Maternal serum cyclophilin A levels in the study group who developed preeclampsia in later follow-up were significantly higher than those of normal healthy pregnant women. CONCLUSION: Cyclophilin A may be a valuable predictor for pregnant women who subsequently develop preeclampsia in their pregnancies.
OBJECTIVE: To investigate cyclophilin A in early second trimester of pregnancy before the onset of preeclampsia. METHODS: In this prospective case-control study, 51 pregnant women whose serum were collected and stored and who developed preeclampsia in later follow-up and 41 pregnant women as control group were included. RESULTS: Maternal serum cyclophilin A levels in the study group who developed preeclampsia in later follow-up were significantly higher than those of normal healthy pregnant women. CONCLUSION: Cyclophilin A may be a valuable predictor for pregnant women who subsequently develop preeclampsia in their pregnancies.
Authors: Elia Shazniza Shaaya; Azyani Yahaya; Muaatamarulain Mustangin; Nurwardah Alfian; Azimatun Noor Aizuddin; Yin Ping Wong; Geok Chin Tan Journal: Int J Environ Res Public Health Date: 2022-04-29 Impact factor: 4.614