You Shang1, Chun Pan2, Xianghong Yang3, Ming Zhong4, Xiuling Shang5, Zhixiong Wu6, Zhui Yu7, Wei Zhang8, Qiang Zhong9, Xia Zheng10, Ling Sang11, Li Jiang12, Jiancheng Zhang1, Wei Xiong1, Jiao Liu13, Dechang Chen14. 1. Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 2. Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China. 3. Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, China. 4. Department of Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China. 5. Department of Critical Care Medicine, Fujian Provincial Hospital, Fujian Provincial Center for Critical Care Medicine, Fuzhou, China. 6. Department of Critical Care Medicine, Huadong Hospital, Shanghai, China. 7. Department of Critical Care Medicine, Renmin Hospital, Wuhan University, Wuhan, China. 8. Emergency Department, the 900th Hospital of Joint Service Corps of Chinese PLA, Fuzhou, China. 9. Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 10. Department of Critical Care Medicine, The First Affiliated Hospital of Zhejiang University, Hangzhou, China. 11. Department of Critical Care Medicine, The 1st Affiliated Hospital of GuangZhou Medical University, GuangZhou Institute of Respiratory Health, Guangzhou, China. 12. Department of Critical Care Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China. 13. Department of Critical Care Medicine, Shanghai Jiaotong University, School of Medicine, Ruijin Hospital North, No. 197 Ruijin 2nd Road, Huangpu District, Shanghai, 201801, China. 14. Department of Critical Care Medicine, Shanghai Jiaotong University, School of Medicine, Ruijin Hospital North, No. 197 Ruijin 2nd Road, Huangpu District, Shanghai, 201801, China. chendechangsh@hotmail.com.
Abstract
BACKGROUND: The ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept all over the world, posing a great pressure on critical care resources due to large number of patients needing critical care. Statements from front-line experts in the field of intensive care are urgently needed. METHODS: Sixteen front-line experts in China fighting against the COVID-19 epidemic in Wuhan were organized to develop an expert statement after 5 rounds of expert seminars and discussions to provide trustworthy recommendation on the management of critically ill COVID-19 patients. Each expert was assigned tasks within their field of expertise to provide draft statements and rationale. Parts of the expert statement are based on epidemiological and clinical evidence, without available scientific evidences. RESULTS: A comprehensive document with 46 statements are presented, including protection of medical personnel, etiological treatment, diagnosis and treatment of tissue and organ functional impairment, psychological interventions, immunity therapy, nutritional support, and transportation of critically ill COVID-19 patients. Among them, 5 recommendations were strong (Grade 1), 21 were weak (Grade 2), and 20 were experts' opinions. A strong agreement from voting participants was obtained for all recommendations. CONCLUSION: There are still no targeted therapies for COVID-19 patients. Dynamic monitoring and supportive treatment for the restoration of tissue vascularization and organ function are particularly important.
BACKGROUND: The ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept all over the world, posing a great pressure on critical care resources due to large number of patients needing critical care. Statements from front-line experts in the field of intensive care are urgently needed. METHODS: Sixteen front-line experts in China fighting against the COVID-19 epidemic in Wuhan were organized to develop an expert statement after 5 rounds of expert seminars and discussions to provide trustworthy recommendation on the management of critically illCOVID-19patients. Each expert was assigned tasks within their field of expertise to provide draft statements and rationale. Parts of the expert statement are based on epidemiological and clinical evidence, without available scientific evidences. RESULTS: A comprehensive document with 46 statements are presented, including protection of medical personnel, etiological treatment, diagnosis and treatment of tissue and organ functional impairment, psychological interventions, immunity therapy, nutritional support, and transportation of critically illCOVID-19patients. Among them, 5 recommendations were strong (Grade 1), 21 were weak (Grade 2), and 20 were experts' opinions. A strong agreement from voting participants was obtained for all recommendations. CONCLUSION: There are still no targeted therapies for COVID-19patients. Dynamic monitoring and supportive treatment for the restoration of tissue vascularization and organ function are particularly important.
Authors: Daniel L Southren; Alexa D Nardone; Adeniran A Haastrup; Russel J Roberts; Marvin G Chang; Edward A Bittner Journal: Nutr Clin Pract Date: 2021-06-08 Impact factor: 3.204