Anja Müller-Lutz1, Benedikt Kamp2, Armin M Nagel3,4,5, Alexandra Ljimani2, Daniel Abrar2, Christoph Schleich2, Lena Wollschläger6, Sven Nebelung2, Hans-Jörg Wittsack2. 1. Department of Diagnostic and Interventional Radiology, Medical Faculty, University Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany. Anja.Lutz@med.uni-duesseldorf.de. 2. Department of Diagnostic and Interventional Radiology, Medical Faculty, University Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany. 3. Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany. 4. Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. 5. Institute of Medical Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany. 6. Department of Orthopedics and Trauma Surgery, Medical Faculty, University Hospital Dusseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Abstract
OBJECTIVE: To measure sodium relaxation times and concentrations in human wrists on a clinical magnetic resonance imaging (MRI) scanner with a density-adapted radial sequence. MATERIALS AND METHODS: Sodium MRI of human wrists was conducted on a 3T MR system using a dual-tuned 1H/23Na surface coil. We performed two studies with 10 volunteers each investigating either sodium T1 (study 1) or sodium T2* (study 2) relaxation times in the radiocarpal joint (RCJ) and midcarpal joint (MCJ). Sodium concentrations of both regions were determined. RESULTS: No differences for transversal of longitudinal relaxation times were found between RCJ and MCJ (T2,s*(RCJ) = (0.9 ± 0.4) ms; T2,s*(MCJ) = (0.9 ± 0.3) ms; T2,l*(RCJ) = (14.9 ± 0.9) ms; T2,l*(MCJ) = (13.9 ± 1.1) ms; T1(RCJ) = (19.0 ± 2.4) ms; T1(MCJ) = (18.5 ± 2.1) ms). Sodium concentrations were (157.7 ± 28.4) mmol/l for study 1 and (159.8 ± 29.1) mmol/l for study 2 in the RCJ, and (172.7 ± 35.6) mmol/l for study 1 and (163.4 ± 26.3) mmol/l for study 2 in the MCJ. CONCLUSION: We successfully determined sodium relaxation times and concentrations of the human wrist on a 3T MRI scanner.
OBJECTIVE: To measure sodium relaxation times and concentrations in human wrists on a clinical magnetic resonance imaging (MRI) scanner with a density-adapted radial sequence. MATERIALS AND METHODS:Sodium MRI of human wrists was conducted on a 3T MR system using a dual-tuned 1H/23Na surface coil. We performed two studies with 10 volunteers each investigating either sodium T1 (study 1) or sodium T2* (study 2) relaxation times in the radiocarpal joint (RCJ) and midcarpal joint (MCJ). Sodium concentrations of both regions were determined. RESULTS: No differences for transversal of longitudinal relaxation times were found between RCJ and MCJ (T2,s*(RCJ) = (0.9 ± 0.4) ms; T2,s*(MCJ) = (0.9 ± 0.3) ms; T2,l*(RCJ) = (14.9 ± 0.9) ms; T2,l*(MCJ) = (13.9 ± 1.1) ms; T1(RCJ) = (19.0 ± 2.4) ms; T1(MCJ) = (18.5 ± 2.1) ms). Sodium concentrations were (157.7 ± 28.4) mmol/l for study 1 and (159.8 ± 29.1) mmol/l for study 2 in the RCJ, and (172.7 ± 35.6) mmol/l for study 1 and (163.4 ± 26.3) mmol/l for study 2 in the MCJ. CONCLUSION: We successfully determined sodium relaxation times and concentrations of the human wrist on a 3T MRI scanner.
Authors: Karl Ludger Radke; Daniel B Abrar; Miriam Frenken; Lena Marie Wilms; Benedikt Kamp; Matthias Boschheidgen; Patrick Liebig; Alexandra Ljimani; Timm Joachim Filler; Gerald Antoch; Sven Nebelung; Hans-Jörg Wittsack; Anja Müller-Lutz Journal: Tomography Date: 2022-05-07
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Authors: Benedikt Kamp; Miriam Frenken; Jan M Henke; Daniel B Abrar; Armin M Nagel; Lena V Gast; Georg Oeltzschner; Lena M Wilms; Sven Nebelung; Gerald Antoch; Hans-Jörg Wittsack; Anja Müller-Lutz Journal: Diagnostics (Basel) Date: 2021-12-08
Authors: Gustav Müller-Franzes; Teresa Nolte; Malin Ciba; Justus Schock; Firas Khader; Andreas Prescher; Lena Marie Wilms; Christiane Kuhl; Sven Nebelung; Daniel Truhn Journal: Diagnostics (Basel) Date: 2022-03-11