Optical sensors based on silver nanoparticles for determination of pharmaceuticals: An overview of advances in the last decade.

This review focuses on optical nanosensors based on silver nanoparticles (Ag NPs) and demonstrates their applications in the determination of pharmaceutical compounds in the last decade. Such optical sensors have received high attention in the analytical field owing to their low cost and simplicity since they do not require any complex or expensive instrumentation. This article reviews Ag NP-based optical methods for the determination of pharmaceutical compounds from 2010 to 2020. The reported optical methods are classified into four types: spectrophotometry, spectrofluorimetry, scattering and chemiluminescence. Ag NPs play different roles in the different sensing platforms used by these methods, the details of which are carefully explained in this review. Moreover, the relevant analytical parameters of the developed methods are categorized by role and tabulated. It is hoped that this review will stimulate further research in this field with similar nanostructures.