Literature DB >> 32497229

Low rate of azole resistance in cases of avian aspergillosis in Germany.

Amelia E Barber1, Sandra Scheufen1, Grit Walther2, Oliver Kurzai1,2, Volker Schmidt3.   

Abstract

Aspergillosis is the most common fungal disease of the avian respiratory tract. Due to delayed diagnosis and treatment failure, the outcome of these infections is often poor. We investigate 159 cases of avian aspergillosis among captive birds in Germany to define clinical features as well as the frequency of in vitro triazole resistance. Adult birds were more likely to present with clinical signs compared to juvenile birds, and dyspnoea was the most common clinical sign, present in 53% of birds. Molecular species identification indicated that all infections were caused by Aspergillus fumigatus. Only one of 159 independent isolates was azole resistant.
© The Author(s) 2020. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.

Entities:  

Keywords:  zzm321990 Aspergillus fumigatuszzm321990 ; avian aspergillosis; azole resistance; veterinary infectious disease

Mesh:

Substances:

Year:  2020        PMID: 32497229     DOI: 10.1093/mmy/myaa045

Source DB:  PubMed          Journal:  Med Mycol        ISSN: 1369-3786            Impact factor:   4.076


  5 in total

1.  Avian-associated Aspergillus fumigatus displays broad phylogenetic distribution, no evidence for host specificity, and multiple genotypes within epizootic events.

Authors:  Lotus A Lofgren; Jeffrey M Lorch; Robert A Cramer; David S Blehert; Brenda M Berlowski-Zier; Megan E Winzeler; Cecilia Gutierrez-Perez; Nicole E Kordana; Jason E Stajich
Journal:  G3 (Bethesda)       Date:  2022-05-06       Impact factor: 3.542

2.  Assessment of the Safety and Efficacy of an Oral Probiotic-Based Vaccine Against Aspergillus Infection in Captive-Bred Humboldt Penguins (Spheniscus humboldti).

Authors:  Milan Thorel; Lourdes Mateos-Hernandez; Baptiste Mulot; Mouna Naila Azzouni; Adnan Hodžić; Hugues Gaillot; Yannick Ruel; Guillaume Desoubeaux; Jean-Baptiste Delaye; Dasiel Obregon; Alejandra Wu-Chuang; José de la Fuente; Luis G Bermúdez-Humarán; Veronica Risco-Castillo; Antoine Leclerc; Alejandro Cabezas-Cruz
Journal:  Front Immunol       Date:  2022-05-13       Impact factor: 8.786

Review 3.  Sterol 14α-Demethylase Ligand-Binding Pocket-Mediated Acquired and Intrinsic Azole Resistance in Fungal Pathogens.

Authors:  Katharina Rosam; Brian C Monk; Michaela Lackner
Journal:  J Fungi (Basel)       Date:  2020-12-22

Review 4.  Emerging Fungal Infections: from the Fields to the Clinic, Resistant Aspergillus fumigatus and Dermatophyte Species: a One Health Perspective on an Urgent Public Health Problem.

Authors:  Antonia Langfeldt; Jeremy A W Gold; Tom Chiller
Journal:  Curr Clin Microbiol Rep       Date:  2022-09-27

Review 5.  Aspergillosis in Wild Birds.

Authors:  Pascal Arné; Veronica Risco-Castillo; Grégory Jouvion; Cécile Le Barzic; Jacques Guillot
Journal:  J Fungi (Basel)       Date:  2021-03-23
  5 in total

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