Literature DB >> 32497131

Comparison of perioperative outcomes in elderly (age ≧ 75 years) vs. younger men undergoing robot-assisted radical prostatectomy.

Yuta Yamada1, Taro Teshima1, Tetsuya Fujimura2, Yusuke Sato1, Masaki Nakamura1, Aya Niimi1,3, Naoki Kimura1, Shigenori Kakutani1,4, Taketo Kawai1, Daisuke Yamada1, Motofumi Suzuki1, Haruki Kume1.   

Abstract

OBJECTIVES: To investigate perioperative, oncologic, and functional outcomes of robot-assisted radical prostatectomy (RARP) in men of age ≥ 75 years in comparison with younger men.
METHODS: From November 2011 to December 2018, six hundred and thirty patients with prostate cancer underwent robot-assisted radical prostatectomy (RARP). A total of 614 patients were analyzed after excluding 16 patients who were treated with hormone therapy prior to RARP. Patients were divided into 2 groups based on their age (age ≥ 75 years: N = 46 patients and age < 75 years: N = 568 patients). Perioperative parameters regarding oncologic/functional outcomes and complication status were compared between the 2 groups. Clavien-Dindo classification was used to classify perioperative complications. Clinical and pathological status including stage, positive margin, continence, and potency status after RARP were analyzed.
RESULTS: Five-hundred sixty-eight and forty-six men were of age <75 and ≥ 75 years, respectively. There were no significant differences between the 2 groups in terms of oncologic outcomes (positive resection margin rate and PSA failure). The duration of hospitalization was longer in older patients but was not statistically significant (P = 0.051). A total number of Clavien ≥3 complications that occurred within a month after RARP were 15 (2.6%) and 2 (4.3%) in younger men (age < 75 years) and older men (age ≥ 75 years), respectively (P = 0.359).
CONCLUSION: The present study showed that the oncologic and surgical outcomes in the elderly group were similar to those in the younger population. However, the duration of hospitalization seemed to be longer in older patients (age ≥ 75 years), despite similar complication rates.

Entities:  

Year:  2020        PMID: 32497131     DOI: 10.1371/journal.pone.0234113

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  3 in total

1.  Advanced age portends poorer prognosis after radical prostatectomy: a single center experience.

Authors:  Antonio Benito Porcaro; Alberto Bianchi; Sebastian Gallina; Emanuele Serafin; Giovanni Mazzucato; Stefano Vidiri; Damiano D'Aietti; Riccardo Rizzetto; Alessandro Tafuri; Clara Cerrato; Andrea Panunzio; Rossella Orlando; Davide Brusa; Matteo Brunelli; Salvatore Siracusano; Maria Angela Cerruto; Alessandro Antonelli
Journal:  Aging Clin Exp Res       Date:  2022-08-17       Impact factor: 4.481

2.  The 'prostate-muscle index': a simple pelvic cavity measurement predicting estimated blood loss and console time in robot-assisted radical prostatectomy.

Authors:  Naoki Kimura; Yuta Yamada; Yuta Takeshima; Masafumi Otsuka; Nobuhiko Akamatsu; Yuji Hakozaki; Jimpei Miyakawa; Yusuke Sato; Yoshiyuki Akiyama; Daisuke Yamada; Tetsuya Fujimura; Haruki Kume
Journal:  Sci Rep       Date:  2022-07-13       Impact factor: 4.996

3.  The Dilemma of Misclassification Rates in Senior Patients With Prostate Cancer, Who Were Treated With Robot-Assisted Radical Prostatectomy: Implications for Patient Counseling and Diagnostics.

Authors:  Nikolaos Liakos; Joern H Witt; Pawel Rachubinski; Sami-Ramzi Leyh-Bannurah
Journal:  Front Surg       Date:  2022-02-16
  3 in total

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